⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10047297 | 0.80 | — | — | |
| SCHEMBL27590469 | 0.77 | — | — | |
| SCHEMBL1008713 | 0.77 | F7 (0.39) | — | |
| SCHEMBL27585811 | 0.75 | EP300 (0.44) | — | |
| SCHEMBL11871573 | 0.74 | ALDH1A1 (0.41) | — | |
| SCHEMBL13424192 | 0.73 | EP300 (0.47) | — | |
| Acrylic Acid SCHEMBL1259561 | 0.73 | LMNA (0.40) | — | |
| SCHEMBL27480029 | 0.73 | — | — | |
| SCHEMBL28188027 | 0.73 | — | — | |
| SCHEMBL4718654 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11512315-B2 | Methods and compositions for macrophage polarization | CODIAK BIOSCIENCES, INC. (US) | 2022-11-29 | — | — | US | disclosed |
| CN-115362185-A | Conjugated diene polymer, conjugated diene polymer composition, rubber crosslinked product, and tire | 瑞住合成橡胶株式会社 | 2022-11-18 | — | — | CN | disclosed |
| US-20210290556-A1 | METHODS OF SUPPRESSING DELIVERY OF EXOSOMES TO LIVER AND SPLEEN | CODIAK BIOSCIENCES, INC. (US) | 2021-09-23 | — | — | US | disclosed |
| US-20200407725-A1 | METHODS AND COMPOSITIONS FOR MACROPHAGE POLARIZATION | CODIAK BIOSCIENCES, INC. (US) | 2020-12-31 | — | — | US | disclosed |
| US-20190264177-A1 | SYNTHETIC MEMBRANE-RECEIVER COMPLEXES | FLAGSHIP VENTURES MANAGEMENT, INC. | 2019-08-29 | — | — | US | disclosed |
| CN-109920843-A | Substrate is doped by the polymer film containing dopant | 加利福尼亚大学董事会 | 2019-06-21 | — | — | CN | disclosed |
| CN-105023833-B | Method for doping a substrate by means of a polymer film containing a dopant | 加利福尼亚大学董事会 | 2019-01-08 | — | — | CN | disclosed |
| EP-3071515-A2 | SYNTHETIC MEMBRANE-RECEIVER COMPLEXES | Rubius Therapeutics, Inc. (US) | 2016-09-28 | — | — | EP | disclosed |
| US-RE45261-E1 | Fatty acid niacin conjugates and their uses | CATABASIS PHARMACEUTICALS, INC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-8815935-B2 | Inhibitors of protein prenyltransferases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-08-26 | — | — | US | disclosed |
| US-20130102639-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-04-25 | — | — | US | disclosed |
| US-8093274-B2 | Inhibitors of protein prenyltransferases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-10 | — | — | US | disclosed |
| US-20110178138-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-07-21 | — | — | US | disclosed |
| US-20100063114-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-03-11 | — | — | US | disclosed |
| US-3998873-A | ORGANOLEPTICS, PERFUMES, AROMAS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-12-21 | — | — | US | disclosed |