SCHEMBL10047622

SCHEMBL10047622

Cc1ccc(N(c2ccc(C)cc2)c2ccc(-c3ccc(-c4ccc(-c5nc6ccccc6s5)cc4)cc3)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 7/20 0.68
RAB9A P51151 4/20 0.56
KDM4E B2RXH2 4/20 0.56
NPC1 O15118 3/20 0.56
GLA P06280 2/20 0.56
GAA P10253 2/20 0.56
MAPT P10636 2/20 0.56
ALDH1A1 P00352 2/20 0.56
MMP9 P14780 2/20 0.56
MMP8 P22894 2/20 0.56
LMNA P02545 1/20 0.56
PAX8 Q06710 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
PKM P14618 1/20 0.56
NOD2 Q9HC29 1/20 0.56
TNF P01375 1/20 0.56
NOD1 Q9Y239 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14195515 1.00 APP (0.68) APPRAB9AKDM4ENPC1GLA
SCHEMBL14195522 0.97 APP (0.65) APPRAB9AKDM4ENPC1GLA
SCHEMBL10029845 0.92 APP (0.73) APPRAB9AKDM4ENPC1GLA
SCHEMBL14195549 0.92 APP (0.73) APPRAB9AKDM4ENPC1GLA
SCHEMBL24155385 0.91 APP (0.76) APPRAB9AKDM4ENPC1GLA
SCHEMBL22007109 0.89 APP (0.69) APPRAB9AKDM4ENPC1GLA
SCHEMBL14195539 0.89 APP (0.69) APPRAB9AKDM4ENPC1GLA
SCHEMBL14195510 0.89 APP (0.69) APPRAB9AKDM4ENPC1GLA
SCHEMBL24156028 0.89 APP (0.69) APPRAB9AKDM4ENPC1GLA
SCHEMBL14952100 0.89 APP (0.69) APPRAB9AKDM4ENPC1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2448925-B1 EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORP (JP) 2017-12-06 EP disclosed
US-20150228907-A1 Porous Films for Use in Light-Emitting Devices NITTO DENKO CORPORATION (JP) 2015-08-13 US disclosed
US-20150228907-A1 Porous Films for Use in Light-Emitting Devices NITTO DENKO CORPORATION (JP) 2015-08-13 US disclosed
US-8952364-B2 Light-emitting devices comprising nanostructures NITTO DENKO CORPORATION (JP) 2015-02-10 US disclosed
US-8952364-B2 Light-emitting devices comprising nanostructures NITTO DENKO CORPORATION (JP) 2015-02-10 US disclosed
US-8927121-B2 Emissive aryl-heteroaryl compounds NITTO DENKO CORPORATION (JP) 2015-01-06 US disclosed
US-8927121-B2 Emissive aryl-heteroaryl compounds NITTO DENKO CORPORATION (JP) 2015-01-06 US disclosed
US-8771845-B2 2014-07-08 US disclosed
US-8771845-B2 2014-07-08 US disclosed
WO-2014036305-A1 POROUS FILMS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2014-03-06 WO disclosed
US-20130284907-A1 EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2013-10-31 US disclosed
US-20130140534-A1 Light-Emitting Devices Comprising Nanostructures NITTO DENKO CORPORATION (JP) 2013-06-06 US disclosed
US-20130140534-A1 Light-Emitting Devices Comprising Nanostructures NITTO DENKO CORPORATION (JP) 2013-06-06 US disclosed
WO-2013068842-A1 LIGHT-EMITTING DEVICES COMPRISING NANOSTRUCTURES NITTO DENKO CORPORATION (JP) 2013-05-16 WO disclosed
WO-2012009283-A1 PHOTOTHERAPY METHODS AND DEVICES COMPRISING EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-01-19 WO disclosed
US-20120015998-A1 PHOTOTHERAPY METHODS AND DEVICES COMPRISING EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-01-19 US disclosed
US-20120015998-A1 PHOTOTHERAPY METHODS AND DEVICES COMPRISING EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-01-19 US disclosed
WO-2011008560-A1 EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2011-01-20 WO disclosed
US-20100326526-A1 EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2010-12-30 US disclosed
US-20100326526-A1 EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2010-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015998-A1 PHOTOTHERAPY METHODS AND DEVICES COMPRISING EMISSIVE ARYL-HETEROARYL COMPOUNDS ARNT, AHR, AR APP 3112/4885RAB9A 2289/4885KDM4E 3036/4885
US-20150228907-A1 Porous Films for Use in Light-Emitting Devices NONO, CLTB, LCP1 APP 1515/4885RAB9A 3395/4885KDM4E 3324/4885
US-20100326526-A1 EMISSIVE ARYL-HETEROARYL COMPOUNDS AHR, AR, ARNT APP 2790/4885RAB9A 879/4885KDM4E 3441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.