Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.64 |
| ▸ | FNTB | P49356 | 5/20 | 0.64 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.64 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13142544 | 1.00 | FNTA (0.64) | FNTAFNTBPGGT1BTRPA1KMT2A | |
| SCHEMBL7617399 | 1.00 | FNTA (0.64) | FNTAFNTBPGGT1BTRPA1KMT2A | |
| SCHEMBL10871808 | 1.00 | FNTA (0.64) | FNTAFNTBPGGT1BTRPA1KMT2A | |
| SCHEMBL795539 | 0.98 | TRPA1 (0.65) | FNTAFNTBPGGT1BTRPA1KMT2A | |
| SCHEMBL795540 | 0.98 | TRPA1 (0.65) | FNTAFNTBPGGT1BTRPA1KMT2A | |
| SCHEMBL13146318 | 0.98 | TRPA1 (0.65) | FNTAFNTBPGGT1BTRPA1KMT2A | |
| SCHEMBL10938865 | 0.87 | FNTA (0.62) | FNTAFNTBPGGT1BTRPA1KMT2A | |
| SCHEMBL2571319 | 0.86 | TRPA1 (0.65) | FNTAFNTBPGGT1BTRPA1KMT2A | |
| SCHEMBL2568553 | 0.86 | TRPA1 (0.65) | FNTAFNTBPGGT1BTRPA1KMT2A | |
| SCHEMBL2568549 | 0.86 | TRPA1 (0.65) | FNTAFNTBPGGT1BTRPA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096393-B1 | GERANYLGERANYLACETAMIDE COMPOUNDS HAVING A PIPERAZINE RING, SALTS THEREOF, PROCESS FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS, AND METHOD OF TREATING ULCERS IN MAMMALS | Nihon Iyakuhin Kogyo Co., Ltd. (JP) | 1986-04-23 | — | — | EP | claimed |
| US-4521417-A | Geranylgeranylacetamide compounds having a piperazine ring, salts thereof, pharmaceutical compositions containing said compounds, and method of treating ulcers in mammals | NIHON IYAKUHIN KOGYO CO., LTD. (JP) | 1985-06-04 | — | — | US | claimed |
| EP-0096393-A1 | Geranylgeranylacetamide compounds having a piperazine ring, salts thereof, process for preparation thereof, pharmaceutical compositions containing said compounds, and method of treating ulcers in mammals | Nihon Iyakuhin Kogyo Co., Ltd. (JP) | 1983-12-21 | — | — | EP | claimed |
| JP-59001474-A | — | — | None | — | — | JP | disclosed |
| EP-2423177-A1 | Analogs of geranylgeranylacetone (GGA) | Nyken Holding B.V. (NL) | 2012-02-29 | — | — | EP | disclosed |
| EP-0096393-B1 | GERANYLGERANYLACETAMIDE COMPOUNDS HAVING A PIPERAZINE RING, SALTS THEREOF, PROCESS FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS, AND METHOD OF TREATING ULCERS IN MAMMALS | Nihon Iyakuhin Kogyo Co., Ltd. (JP) | 1986-04-23 | — | — | EP | disclosed |
| EP-0096393-B1 | GERANYLGERANYLACETAMIDE COMPOUNDS HAVING A PIPERAZINE RING, SALTS THEREOF, PROCESS FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS, AND METHOD OF TREATING ULCERS IN MAMMALS | Nihon Iyakuhin Kogyo Co., Ltd. (JP) | 1986-04-23 | — | — | EP | disclosed |
| US-4521417-A | Geranylgeranylacetamide compounds having a piperazine ring, salts thereof, pharmaceutical compositions containing said compounds, and method of treating ulcers in mammals | NIHON IYAKUHIN KOGYO CO., LTD. (JP) | 1985-06-04 | — | — | US | disclosed |
| US-4521417-A | Geranylgeranylacetamide compounds having a piperazine ring, salts thereof, pharmaceutical compositions containing said compounds, and method of treating ulcers in mammals | NIHON IYAKUHIN KOGYO CO., LTD. (JP) | 1985-06-04 | — | — | US | disclosed |
| US-4521417-A | Geranylgeranylacetamide compounds having a piperazine ring, salts thereof, pharmaceutical compositions containing said compounds, and method of treating ulcers in mammals | NIHON IYAKUHIN KOGYO CO., LTD. (JP) | 1985-06-04 | — | — | US | disclosed |
| JP-S591474-A | GERANYLGERANYLACETAMIDE COMPOUND HAVING PIPERAZINE RING OR SALT THEREOF | NIPPON IYAKUHIN KOGYO KK | 1984-01-06 | — | — | JP | disclosed |
| EP-0096393-A1 | Geranylgeranylacetamide compounds having a piperazine ring, salts thereof, process for preparation thereof, pharmaceutical compositions containing said compounds, and method of treating ulcers in mammals | Nihon Iyakuhin Kogyo Co., Ltd. (JP) | 1983-12-21 | — | — | EP | disclosed |
| EP-0096393-A1 | Geranylgeranylacetamide compounds having a piperazine ring, salts thereof, process for preparation thereof, pharmaceutical compositions containing said compounds, and method of treating ulcers in mammals | Nihon Iyakuhin Kogyo Co., Ltd. (JP) | 1983-12-21 | — | — | EP | disclosed |
| EP-0096393-A1 | Geranylgeranylacetamide compounds having a piperazine ring, salts thereof, process for preparation thereof, pharmaceutical compositions containing said compounds, and method of treating ulcers in mammals | Nihon Iyakuhin Kogyo Co., Ltd. (JP) | 1983-12-21 | — | — | EP | disclosed |