SCHEMBL7617399

SCHEMBL7617399

CC(=O)NCC=C(C)CCC=C(C)CCC=C(C)C

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FNTA P49354 7/20 0.64
FNTB P49356 5/20 0.64
PGGT1B P53609 3/20 0.64
TRPA1 O75762 1/20 0.63
KMT2A Q03164 2/20 0.59
TRPV1 Q8NER1 3/20 0.55
MAPT P10636 2/20 0.53
ALDH1A1 P00352 1/20 0.53
MEN1 O00255 1/20 0.53
CYP3A4 P08684 1/20 0.53
ALOX15 P16050 1/20 0.53
UGT1A1 P22309 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10048261 1.00 FNTA (0.64) FNTAFNTBPGGT1BTRPA1KMT2A
SCHEMBL13142544 1.00 FNTA (0.64) FNTAFNTBPGGT1BTRPA1KMT2A
SCHEMBL10871808 1.00 FNTA (0.64) FNTAFNTBPGGT1BTRPA1KMT2A
SCHEMBL795539 0.98 TRPA1 (0.65) FNTAFNTBPGGT1BTRPA1KMT2A
SCHEMBL795540 0.98 TRPA1 (0.65) FNTAFNTBPGGT1BTRPA1KMT2A
SCHEMBL13146318 0.98 TRPA1 (0.65) FNTAFNTBPGGT1BTRPA1KMT2A
SCHEMBL10938865 0.87 FNTA (0.62) FNTAFNTBPGGT1BTRPA1KMT2A
SCHEMBL2571319 0.86 TRPA1 (0.65) FNTAFNTBPGGT1BTRPA1KMT2A
SCHEMBL2568553 0.86 TRPA1 (0.65) FNTAFNTBPGGT1BTRPA1KMT2A
SCHEMBL2568549 0.86 TRPA1 (0.65) FNTAFNTBPGGT1BTRPA1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4303588-A ANTIBACTERIAL, ANTIULCER AGENTS KURARAY CO., LTD. (JP) 1981-12-01 US claimed
JP-55129275-A None JP disclosed
EP-0556394-B1 LYOPHILIZED PREPARATION AND PRODUCTION THEREOF NIPPON SHINYAKU CO LTD (JP) 2002-06-19 EP disclosed
US-5651991-A FATTY EMULSION OF NON-LIPOSOME PARTICLES CONTAINING DRUG IN CORE, AND HAVING LIPID SURFACE LAYER NIPPON SHINYAKU CO. LTD. (JP) 1997-07-29 US disclosed
US-5635491-A Lyophilized fatty emulsions and a process for the production thereof NIPPON SHINYAKU CO., LTD. (JP) 1997-06-03 US disclosed
EP-0315079-B1 Drug carriers NIPPON SHINYAKU CO LTD (JP) 1995-03-01 EP disclosed
EP-0556394-A1 LYOPHILIZED PREPARATION AND PRODUCTION THEREOF NIPPON SHINYAKU COMPANY, LIMITED (JP) 1993-08-25 EP disclosed
EP-0315079-A1 Drug carriers NIPPON SHINYAKU COMPANY, LIMITED (JP) 1989-05-10 EP disclosed
EP-0096393-B1 GERANYLGERANYLACETAMIDE COMPOUNDS HAVING A PIPERAZINE RING, SALTS THEREOF, PROCESS FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS, AND METHOD OF TREATING ULCERS IN MAMMALS Nihon Iyakuhin Kogyo Co., Ltd. (JP) 1986-04-23 EP disclosed
US-4521417-A Geranylgeranylacetamide compounds having a piperazine ring, salts thereof, pharmaceutical compositions containing said compounds, and method of treating ulcers in mammals NIHON IYAKUHIN KOGYO CO., LTD. (JP) 1985-06-04 US disclosed
EP-0096393-A1 Geranylgeranylacetamide compounds having a piperazine ring, salts thereof, process for preparation thereof, pharmaceutical compositions containing said compounds, and method of treating ulcers in mammals Nihon Iyakuhin Kogyo Co., Ltd. (JP) 1983-12-21 EP disclosed
US-4303588-A ANTIBACTERIAL, ANTIULCER AGENTS KURARAY CO., LTD. (JP) 1981-12-01 US disclosed
US-4303588-A ANTIBACTERIAL, ANTIULCER AGENTS KURARAY CO., LTD. (JP) 1981-12-01 US disclosed
US-4303588-A ANTIBACTERIAL, ANTIULCER AGENTS KURARAY CO., LTD. (JP) 1981-12-01 US disclosed
JP-S55129275-A FARNESYLACETIC ACID AMIDE BEARING PIPERAZINE RING OR ITS SALT KURARAY CO LTD 1980-10-06 JP disclosed