Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FPR3 | P25089 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14400824 | 1.00 | LMNA (0.51) | LMNAKDM4EEPHX2THRBESR1 | |
| SCHEMBL14611026 | 0.85 | KDM4E (0.46) | LMNAKDM4EEPHX2THRBESR1 | |
| SCHEMBL5395258 | 0.84 | KDM4E (0.56) | LMNAKDM4EEPHX2THRBESR1 | |
| SCHEMBL11064771 | 0.82 | KDM4E (0.61) | LMNAKDM4EEPHX2THRBESR1 | |
| SCHEMBL11064769 | 0.82 | KDM4E (0.61) | LMNAKDM4EEPHX2THRBESR1 | |
| SCHEMBL21389659 | 0.81 | KDM4E (0.53) | LMNAKDM4EEPHX2ESR1 | |
| SCHEMBL19786751 | 0.81 | KDM4E (0.53) | LMNAKDM4EEPHX2ESR1 | |
| SCHEMBL14392991 | 0.80 | KDM4E (0.59) | LMNAKDM4EEPHX2THRBESR1 | |
| SCHEMBL10124090 | 0.80 | KDM4E (0.59) | LMNAKDM4EEPHX2THRBESR1 | |
| SCHEMBL25361995 | 0.79 | KDM4E (0.54) | LMNAKDM4EEPHX2THRBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124050-B2 | Method for coating the internal surface of a reaction vessel | HAMMERSMITH IMANET LIMITED (GB) | 2012-02-28 | — | — | US | disclosed |
| EP-1697047-B1 | METHOD FOR COATING THE INTERNAL SURFACE OF A REACTION VESSEL | HAMMERSMITH IMANET LTD (GB) | 2009-06-17 | — | — | EP | disclosed |