SCHEMBL10049050

SCHEMBL10049050

Nc1ccc(Oc2ccc(C3CCC(O)CC3)cc2)c(N)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.44
CYP2C9 P11712 3/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
CYP2D6 P10635 2/20 0.40
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CYP3A4 P08684 3/20 0.39
KCNH2 Q12809 2/20 0.39
HRH3 Q9Y5N1 1/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
SLC18A3 Q16572 1/20 0.38
SCN8A Q9UQD0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21756941 0.93 MAPT (0.45) CYP2C9CYP1A2CYP2C19CYP2D6MAPT
SCHEMBL12220514 0.86 ESR2 (0.42) ESR2CYP2C9CYP1A2CYP2C19CYP2D6
SCHEMBL5682640 0.85 HAO1 (0.43) CYP2C9CYP1A2CYP2C19CYP2D6MAPT
SCHEMBL10033588 0.83 SMN1; SMN2 (0.38) CYP2C9CYP1A2CYP2C19CYP2D6MAPT
SCHEMBL21765332 0.83 MAPT (0.45) CYP2C9CYP1A2CYP2C19CYP2D6MAPT
SCHEMBL17722779 0.82 MAPT (0.37) CYP2C9CYP1A2CYP2C19CYP2D6MAPT
SCHEMBL17720303 0.82 ESR2 (0.40) ESR2CYP2C9CYP1A2CYP2C19CYP2D6
SCHEMBL10017553 0.82 SLC6A4 (0.41) CYP2C9CYP1A2CYP2C19CYP2D6MAPT
SCHEMBL13910064 0.80 SLC6A2 (0.40) CYP2C9CYP1A2CYP2C19CYP2D6MAPT
SCHEMBL16171980 0.80 CYP2C9 (0.47) ESR2CYP2C9CYP1A2CYP2C19CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523889-B2 Liquid crystal display unit and method of manufacturing the same SONY CORPORATION (JP) 2016-12-20 US disclosed
US-9507210-B2 Liquid crystal display and method of manufacturing the same SONY CORPORATION (JP) 2016-11-29 US disclosed
US-9470929-B2 Liquid crystal display unit and method of manufacturing the same SONY CORPORATION (JP) 2016-10-18 US disclosed
US-9366910-B2 Liquid crystal display and method of manufacturing the same SONY CORPORATION (JP) 2016-06-14 US disclosed
US-20160011463-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2016-01-14 US disclosed
US-9146425-B2 Liquid crystal display and method of manufacturing the same SONY CORPORATION (JP) 2015-09-29 US disclosed
US-20150146148-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2015-05-28 US disclosed
US-20140170926-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2014-06-19 US disclosed
US-20130155360-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2013-06-20 US disclosed
US-20130010244-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION 2013-01-10 US disclosed
US-20120212697-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SONY CORPORATION (JP) 2012-08-23 US disclosed
US-20120026440-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING THE SAME SONY CORPORATION (JP) 2012-02-02 US disclosed
US-20110273652-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-11-10 US disclosed
US-20110157531-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160011463-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME PYM1, PDCD2L, SDAD1 ESR2 4689/4885CYP2C9 3211/4885CYP1A2 3787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.