Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21756941 | 0.90 | MAPT (0.45) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21756889 | 0.84 | ALDH1A1 (0.43) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12220514 | 0.83 | ESR2 (0.42) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10049050 | 0.83 | ESR2 (0.44) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5682640 | 0.83 | HAO1 (0.43) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10033588 | 0.81 | SMN1; SMN2 (0.38) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10017553 | 0.80 | SLC6A4 (0.41) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17722779 | 0.80 | MAPT (0.37) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17720303 | 0.80 | ESR2 (0.40) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21770055 | 0.80 | ALDH1A1 (0.61) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039094-A1 | PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERATIVE ACTIVITY | Xeniopro GmbH (DE) | 2020-02-27 | — | — | WO | disclosed |
| WO-2020039088-A2 | NOVEL COMPOUNDS | Xeniopro GmbH (DE) | 2020-02-27 | — | — | WO | disclosed |