SCHEMBL10049286

SCHEMBL10049286

FC(F)=Cc1ccccc1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 2/20 0.46
GRIN3B O60391 2/20 0.46
GRIN1 Q05586 2/20 0.46
GRIN2A Q12879 2/20 0.46
GRIN2B Q13224 2/20 0.46
GRIN2C Q14957 2/20 0.46
GRIN3A Q8TCU5 2/20 0.46
ALDH1A1 P00352 3/20 0.43
HSD17B10 Q99714 2/20 0.43
HPGD P15428 1/20 0.43
BCL2L1 Q07817 1/20 0.43
BACE1 P56817 2/20 0.39
CYP2A6 P11509 1/20 0.38
MAPK1 P28482 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
BCAT2 O15382 1/20 0.36
CYP26A1 O43174 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24311192 0.83 PDCD1 (0.49) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30204270 0.81 KIF11 (0.47) ALDH1A1HSD17B10BACE1
SCHEMBL28419453 0.80 GRIN2D (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9441680 0.78 GRIN2D (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL13032947 0.78 NFE2L2 (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30175418 0.77 FFAR4 (0.41) GRIN2B
SCHEMBL29801710 0.77 GRIN2D (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL828196 0.77 GRIN2D (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2841427 0.76 GRIN2D (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL8166983 0.76 GRIN2D (0.43) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082240-B Succinate dehydrogenase inhibitor and synthesis method and application thereof 华中农业大学 2025-04-01 CN disclosed
CN-116082240-A Succinate dehydrogenase inhibitor and synthesis method and application thereof 华中农业大学 2023-05-09 CN disclosed
CN-115948752-A Reaction method for selective fluorination functionalization of harmonious difluoro olefin 暨南大学 2023-04-11 CN disclosed
CN-115572210-B (1,2,2,2-tetrafluoroethyl) arene derivative and preparation method and application thereof 暨南大学 2023-03-21 CN disclosed
CN-115572210-A (1, 2-tetrafluoroethyl) arene derivative and preparation method and application thereof 暨南大学 2023-01-06 CN disclosed
CN-107324970-B Crosslinking agent and fluorine-containing aromatic compound 霓佳斯株式会社 2021-06-29 CN disclosed
CN-106574074-B Crosslinking agent and fluorine-containing aromatic compound 霓佳斯株式会社 2020-06-23 CN disclosed
US-8148006-B2 Electrolytic solution and battery SONY CORPORATION (JP) 2012-04-03 US disclosed
US-8148006-B2 Electrolytic solution and battery SONY CORPORATION (JP) 2012-04-03 US disclosed