Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.54 |
| ▸ | NQO2 | P16083 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11842024 | 0.79 | ALDH1A1 (0.59) | PTGS1PTGS2NQO2ALDH1A1MAPT | |
| SCHEMBL21758555 | 0.78 | PTGS1 (0.49) | PTGS1PTGS2NQO2ALDH1A1MAPT | |
| SCHEMBL6247478 | 0.77 | CYP2A6 (0.41) | PTGS1PTGS2MAPTCYP3A4CYP2C9 | |
| SCHEMBL1758882 | 0.77 | CYP2A6 (0.41) | PTGS1PTGS2MAPTCYP3A4CYP2C9 | |
| SCHEMBL28660052 | 0.77 | ESR1 (0.59) | PTGS1PTGS2NQO2ALDH1A1MAPT | |
| SCHEMBL1758883 | 0.77 | CYP2A6 (0.41) | PTGS1PTGS2MAPTCYP3A4CYP2C9 | |
| SCHEMBL14001486 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL18483455 | 0.75 | CYP19A1 (0.41) | ALDH1A1MAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL6770445 | 0.75 | KMT2A (0.49) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL14419183 | 0.75 | TRPA1 (0.58) | PTGS2MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153615-B2 | Synthesis of glycerolipid carbamates and dicarbamates and their use as an antitumor compounds | THE UNIVERSITY OF MANITOBA (CA) | 2012-04-10 | — | — | US | disclosed |
| US-20090042811-A1 | Synthesis of Glycerolipid Carbamates and Dicarbamates and Their Use as an Antitumor Compounds | THE UNIVERSITY OF MANITOBA (CA) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042811-A1 | Synthesis of Glycerolipid Carbamates and Dicarbamates and Their Use as an Antitumor Compounds | PHOSPHO1, SGMS1, UGCG | PTGS1 1559/4885PTGS2 2401/4885NQO2 789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.