Sugi Predict

Sugi Predict / Compounds / SCHEMBL10049669

SCHEMBL10049669

SCHEMBL10049669

Brc1ccc(-c2ccc3c(c2)c2cc(-c4ccc5c(c4)c4cc(-c6ccc(Br)cc6)ccc4n5-c4ccccc4)ccc2n3-c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.48
▸ KDM4E B2RXH2 1/20 0.48
▸ ATM Q13315 1/20 0.48
▸ ALDH1A1 P00352 3/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ RXFP1 Q9HBX9 3/20 0.44
▸ MEN1 O00255 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ NPC1 O15118 3/20 0.37
▸ RAB9A P51151 3/20 0.37
▸ NFKB1 P19838 1/20 0.37
▸ NFKB2 Q00653 1/20 0.37
▸ RELA Q04206 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ HDAC4 P56524 1/20 0.37
▸ EGFR P00533 1/20 0.36
▸ ERBB2 P04626 1/20 0.36
▸ NLRP3 Q96P20 1/20 0.36
▸ JAK2 O60674 1/20 0.35
▸ JAK3 P52333 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12619981 1.00 L3MBTL1 (0.48) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL3388459 0.98 ALDH1A1 (0.52) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL29456821 0.95 L3MBTL1 (0.58) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL30580491 0.95 L3MBTL1 (0.58) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL854324 0.95 L3MBTL1 (0.58) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL9916946 0.95 L3MBTL1 (0.58) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL9916950 0.95 L3MBTL1 (0.58) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL17194700 0.95 ALDH1A1 (0.48) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL31122338 0.95 ALDH1A1 (0.52) L3MBTL1KDM4EATMALDH1A1MAPK1
SCHEMBL17742564 0.95 ALDH1A1 (0.52) L3MBTL1KDM4EATMALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2603541-B1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2021-04-21 — — EP disclosed
EP-2603540-B1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2021-04-21 — — EP disclosed
US-9583717-B2 Compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-02-28 — — US disclosed
US-9583717-B2 Compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-02-28 — — US disclosed
US-9102797-B2 Polymers with carbazole structural units MERCK PATENT GMBH (DE) 2015-08-11 — — US disclosed
US-9102797-B2 Polymers with carbazole structural units MERCK PATENT GMBH (DE) 2015-08-11 — — US disclosed
US-8969512-B2 Polymers having carbazole structural units MERCK PATENT GMBH (DE) 2015-03-03 — — US disclosed
US-8969512-B2 Polymers having carbazole structural units MERCK PATENT GMBH (DE) 2015-03-03 — — US disclosed
US-20140138661-A1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-05-22 — — US disclosed
US-20140138661-A1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-05-22 — — US disclosed
US-20130150527-A1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS SAMSUNG DISPLAY CO., LTD. (KR) 2013-06-13 — — US disclosed
US-20130150527-A1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS SAMSUNG DISPLAY CO., LTD. (KR) 2013-06-13 — — US disclosed
US-20130137818-A1 POLYMERS HAVING CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2013-05-30 — — US disclosed
US-20130137818-A1 POLYMERS HAVING CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2013-05-30 — — US disclosed
WO-2012019724-A1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2012-02-16 — — WO disclosed