SCHEMBL10050147

SCHEMBL10050147

[C-]#[N+]c1ccc(C#N)cc1C=Cc1ccc(N(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.41
TRPA1 O75762 1/20 0.41
TRPM8 Q7Z2W7 4/20 0.39
NFE2L2 Q16236 4/20 0.38
RELA Q04206 4/20 0.38
CYP1A1 P04798 3/20 0.38
CYP1A2 P05177 3/20 0.38
CYP1B1 Q16678 3/20 0.38
SLC16A3 O15427 1/20 0.37
SLC16A1 P53985 1/20 0.37
APP P05067 1/20 0.35
ESR1 P03372 2/20 0.35
ABL1 P00519 1/20 0.35
TTR P02766 1/20 0.35
ABCB1 P08183 1/20 0.35
ALOX5 P09917 1/20 0.35
BCR P11274 1/20 0.35
CYP19A1 P11511 1/20 0.35
NQO2 P16083 1/20 0.35
PTGS2 P35354 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10050148 0.96 NFE2L2 (0.39) SNCATRPA1NFE2L2RELACYP1A1
SCHEMBL10050149 0.87 SNCA (0.35) SNCATRPA1NFE2L2RELACYP1A1
SCHEMBL10074799 0.86 TRPA1 (0.46) SNCATRPA1TRPM8NFE2L2RELA
SCHEMBL12258572 0.85 TRPA1 (0.43) SNCATRPA1TRPM8RELACYP1A1
SCHEMBL12087833 0.83 SNCA (0.36) SNCAAPP
SCHEMBL12258700 0.81 TRPA1 (0.37) SNCATRPA1TRPM8NFE2L2RELA
SCHEMBL10074801 0.81 NFE2L2 (0.43) SNCATRPA1NFE2L2RELACYP1A1
SCHEMBL12258581 0.80 ESR1 (0.43) TRPA1RELACYP1A1CYP1A2CYP1B1
SCHEMBL18327869 0.80 TRPA1 (0.51) TRPA1TRPM8NFE2L2RELACYP1A1
SCHEMBL830304 0.80 TRPA1 (0.51) TRPA1TRPM8NFE2L2RELACYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956736-B2 Organic electroluminescent device and display apparatus SONY CORPORATION (JP) 2015-02-17 US disclosed
US-8207088-B2 Transfer substrate and method for fabricating organic electroluminescent element SONY CORPORATION (JP) 2012-06-26 US disclosed
US-8025986-B2 Light emitting region having a charge-transport, amine-containing steryl compound like 1-((2,5-dicyano)phenyl)ethylene-),4- ((p-methoxy-)phenyl)-amino(-(phenyl)benzene; heat resistance; accuracy; high purity and luminescence in long wavelength range (red); flat display panel; television SONY CORPORATION (JP) 2011-09-27 US disclosed
US-20090045735-A1 TRANSFER SUBSTRATE AND METHOD FOR FABRICATING ORGANIC ELECTROLUMINESCENT ELEMENT SONY CORPORATION (JP) 2009-02-19 US disclosed
US-20090039769-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2009-02-12 US disclosed
US-20080164809-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2008-07-10 US disclosed