SCHEMBL10050322

SCHEMBL10050322

CNC(=O)C(C)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.33
PDK1 Q15118 6/20 0.32
PDK2 Q15119 6/20 0.32
PDK3 Q15120 6/20 0.32
PDK4 Q16654 6/20 0.32
ABCC9 O60706 1/20 0.31
ABCC8 Q09428 1/20 0.31
KCNJ11 Q14654 1/20 0.31
KCNJ8 Q15842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19537494 0.78 CA2 (0.33) CA2PDK1PDK2PDK3PDK4
SCHEMBL10064046 0.77
SCHEMBL15993816 0.77
SCHEMBL15598617 0.74 CA2 (0.35) CA2
SCHEMBL27287425 0.74 CA2 (0.35) CA2
SCHEMBL7706692 0.74 MEN1 (0.31) CA2PDK1PDK2PDK3PDK4
SCHEMBL7703194 0.74 MEN1 (0.31) CA2PDK1PDK2PDK3PDK4
SCHEMBL312534 0.73
SCHEMBL13687261 0.72 CA2 (0.33) CA2PDK1PDK2PDK3PDK4
SCHEMBL9532010 0.72 CA2 (0.33) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160222170-A1 PHOTO-CURABLE FLUOROPOLYETHER-BASED RUBBER COMPOSITION, CURING METHOD THEREOF AND CURED PRODUCT OBTAINED BY THE CURING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-08-04 US disclosed
US-8492487-B2 Thermosetting fluoropolyether adhesive composition and adhesion method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
US-8299196-B2 Adhesive composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-10-30 US disclosed
US-20110257315-A1 ADHESIVE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-10-20 US disclosed