Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703194 | 1.00 | MEN1 (0.31) | MEN1GAAKMT2AHSD17B10CA2 | |
| SCHEMBL10050322 | 0.74 | CA2 (0.33) | CA2PDK1PDK2PDK3PDK4 | |
| SCHEMBL19537494 | 0.74 | CA2 (0.33) | CA2PDK1PDK2PDK3PDK4 | |
| SCHEMBL10064046 | 0.73 | — | — | |
| SCHEMBL15993816 | 0.73 | — | — | |
| SCHEMBL2190296 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL19900815 | 0.70 | — | — | |
| SCHEMBL6439749 | 0.70 | LMNA (0.32) | KMT2A | |
| SCHEMBL6439208 | 0.70 | ALDH1A1 (0.40) | MEN1KMT2A | |
| SCHEMBL14209831 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020039769-A1 | Process for preparing optically active 3,3,3- trifluoromethyl-2-alkylpropionic acid derivatives | LONZA AG | 2002-04-04 | — | — | US | disclosed |