SCHEMBL10050909

SCHEMBL10050909

CC(C)=CC(C(N)=O)=C(C)C

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
ALOX15 P16050 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
CRBN Q96SW2 1/20 0.33
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18571032 0.83 LMNA (0.37) LMNAALOX15BLMPMP22TDP1
SCHEMBL31538060 0.77 TSHR (0.35)
SCHEMBL10454892 0.74 FFAR3 (0.33)
SCHEMBL18570790 0.74 TDP1 (0.32) TDP1
SCHEMBL22996509 0.72
SCHEMBL13895763 0.71
SCHEMBL23230296 0.70 LMNA (0.35) LMNAALOX15BLMPMP22TDP1
SCHEMBL569588 0.69
SCHEMBL7681046 0.69
SCHEMBL13648015 0.69 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120326348-A1 Polymer Mechanical Damping Composites And Methods of Production FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2012-12-27 US disclosed
US-20120320123-A1 INK SET AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2012-12-20 US disclosed
US-8314158-B2 Compacted polyelectrolyte complexes and articles The Florida State University Research Foundation, Inc. (US) 2012-11-20 US disclosed
US-20120238642-A1 Polymer Mechanical Damping Composites and Methods of Production FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2012-09-20 US disclosed
US-20120160118-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2012-06-28 US disclosed
US-20120108684-A1 COMPACTED POLYELECTROLYTE COMPLEXES AND ARTICLES FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2012-05-03 US disclosed
US-8124317-B2 Planographic printing plate precursor and method of producing a copolymer used therein FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-20110259571-A1 HYDROPHILIC COMPOSITION AND HYDROPHILIC MEMBER HAVING ANTIFUNGAL PROPERTY FUJIFILM CORPORATION (JP) 2011-10-27 US disclosed
US-20090087787-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PRODUCING A COPOLYMER USED THEREIN FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20070149742-A1 Hydrophilic composition and hydrophilic member FUJIFILM CORPORATION 2007-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120238642-A1 Polymer Mechanical Damping Composites and Methods of Production PUF60, PARG, PARN LMNA 288/4885ALOX15 4413/4885BLM 16/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.