SCHEMBL10051134

SCHEMBL10051134

Cc1ccc(CN(C)CCN)cc1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CARM1 Q86X55 5/20 0.68
▸ PRMT6 Q96LA8 3/20 0.68
▸ PRMT8 Q9NR22 2/20 0.68
▸ PRMT1 Q99873 4/20 0.55
▸ PYCR1 P32322 2/20 0.53
▸ CYP1A2 P05177 1/20 0.50
▸ CYP2A6 P11509 1/20 0.50
▸ TAAR1 Q96RJ0 1/20 0.50
▸ NPSR1 Q6W5P4 1/20 0.50
▸ KDM4E B2RXH2 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ KCNH2 Q12809 1/20 0.40
▸ SIGMAR1 Q99720 1/20 0.39
▸ AGXT P21549 1/20 0.39
▸ CYP2C19 P33261 1/20 0.38
▸ PRMT3 O60678 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16312619 0.82 PYCR1 (0.65) PYCR1CYP1A2CYP2A6TAAR1NPSR1
SCHEMBL23615993 0.82 CARM1 (0.66) CARM1PRMT6PRMT8PRMT1PYCR1
SCHEMBL27909746 0.81 CYP1A2 (0.52) CARM1PRMT6PRMT8PRMT1PYCR1
SCHEMBL10065870 0.81 PYCR1 (0.55) CARM1PRMT6PRMT8PYCR1CYP1A2
SCHEMBL1395704 0.81 CARM1 (1.00) CARM1PRMT6PRMT8PRMT1PYCR1
SCHEMBL9147668 0.80 CARM1 (0.63) CARM1PRMT6PRMT8PRMT1PYCR1
SCHEMBL5028754 0.79 PYCR1 (0.53) CARM1PRMT6PRMT8PYCR1NPSR1
SCHEMBL22537476 0.79 PYCR1 (0.53) CARM1PRMT6PRMT8PRMT1PYCR1
SCHEMBL14373882 0.79 PYCR1 (0.53) CARM1PRMT6PRMT8PYCR1NPSR1
Hydrochloric Acid SCHEMBL17372655 0.79 CARM1 (0.96) CARM1PRMT6PRMT8PRMT1PYCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8317999-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-11-27 — — US disclosed
US-8313639-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-11-20 — — US disclosed
US-8293082-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-10-23 — — US disclosed
US-20120071363-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2012-03-22 — — US disclosed
US-20110248319-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2011-10-13 — — US disclosed
US-20110247933-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2011-10-13 — — US disclosed
US-20110241081-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2011-10-06 — — US disclosed
US-20110230375-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2011-09-22 — — US disclosed
US-20090026082-A1 Methods and apparatus for measuring analytes using large scale FET arrays ION TORRENT SYSTEMS INCORPORATED (US) 2009-01-29 — — US disclosed
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