Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 7/20 | 0.63 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.63 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 6/20 | 0.39 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10051134 | 0.80 | CARM1 (0.68) | CARM1PRMT6PRMT8ALDH1A1KDM4E | |
| SCHEMBL23615993 | 0.78 | CARM1 (0.66) | CARM1PRMT6PRMT8ALDH1A1KDM4E | |
| SCHEMBL1395704 | 0.78 | CARM1 (1.00) | CARM1PRMT6PRMT8ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL17372655 | 0.76 | CARM1 (0.96) | CARM1PRMT6PRMT8ALDH1A1KDM4E | |
| SCHEMBL17312007 | 0.76 | CARM1 (0.61) | CARM1PRMT6PRMT8ALDH1A1PYCR1 | |
| SCHEMBL7186148 | 0.75 | ALDH1A1 (0.48) | CARM1PRMT6PRMT8ALDH1A1PRMT1 | |
| SCHEMBL22542480 | 0.74 | TAAR1 (0.41) | CARM1PRMT6PRMT8ALDH1A1KDM4E | |
| SCHEMBL5188252 | 0.74 | AOC3 (0.44) | CARM1ALDH1A1KDM4EPRMT1 | |
| SCHEMBL4378410 | 0.74 | TAAR1 (0.42) | CARM1PRMT6PRMT8ALDH1A1KDM4E | |
| SCHEMBL29426388 | 0.74 | APP (0.41) | CARM1PRMT6PRMT8PYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660819-A1 | NEW N,N,N',N'-TETRASUBSTITUTED-1,2-ETHANEDIAMINE DERIVATIVE COMPOUNDS. | FERRER INT (ES) | 1995-07-05 | — | — | EP | disclosed |