Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13913105 | 1.00 | LCK (0.48) | LCKNFKB1CA12CA1CA2 | |
| SCHEMBL13748668 | 1.00 | LCK (0.48) | LCKNFKB1CA12CA1CA2 | |
| SCHEMBL713874 | 1.00 | LCK (0.48) | LCKNFKB1CA12CA1CA2 | |
| SCHEMBL17123444 | 0.96 | LCK (0.46) | LCKNFKB1CA12CA1CA2 | |
| SCHEMBL15790833 | 0.96 | LCK (0.46) | LCKNFKB1CA12CA1CA2 | |
| SCHEMBL2055292 | 0.96 | LCK (0.46) | LCKNFKB1CA12CA1CA2 | |
| SCHEMBL3319406 | 0.96 | LCK (0.46) | LCKNFKB1CA12CA1CA2 | |
| SCHEMBL2609752 | 0.96 | LCK (0.46) | LCKNFKB1CA12CA1CA2 | |
| SCHEMBL3320230 | 0.96 | LCK (0.46) | LCKNFKB1CA12CA1CA2 | |
| SCHEMBL62173 | 0.96 | NFKB1 (0.46) | LCKNFKB1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028855-A1 | SHALE HYDRATION INHIBITION AGENT(S) AND METHOD OF USE | SHRIEVE CHEMICAL PRODUCTS (US) | 2012-02-02 | — | — | US | disclosed |
| US-8026198-B2 | Shale hydration inhibition agent(s) and method of use | SHRIEVE CHEMICAL PRODUCTS, INC. | 2011-09-27 | — | — | US | disclosed |
| US-20090247429-A1 | SHALE HYDRATION INHIBITION AGENT(S) AND METHOD OF USE | SHRIEVE CHEMICAL PRODUCTS, INC. (US) | 2009-10-01 | — | — | US | disclosed |