Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714869 | 1.00 | LCK (0.76) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL13844443 | 0.97 | LCK (0.73) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL15591992 | 0.94 | LCK (0.70) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL2425755 | 0.94 | LCK (0.68) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL714217 | 0.91 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL714027 | 0.91 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL17038665 | 0.91 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL15591979 | 0.91 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL15591987 | 0.91 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL15591981 | 0.91 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028855-A1 | SHALE HYDRATION INHIBITION AGENT(S) AND METHOD OF USE | SHRIEVE CHEMICAL PRODUCTS (US) | 2012-02-02 | — | — | US | disclosed |
| US-8026198-B2 | Shale hydration inhibition agent(s) and method of use | SHRIEVE CHEMICAL PRODUCTS, INC. | 2011-09-27 | — | — | US | disclosed |
| US-20090247429-A1 | SHALE HYDRATION INHIBITION AGENT(S) AND METHOD OF USE | SHRIEVE CHEMICAL PRODUCTS, INC. (US) | 2009-10-01 | — | — | US | disclosed |