Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15591987 | 0.97 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL15591981 | 0.97 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL15591979 | 0.97 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL17038665 | 0.97 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL714217 | 0.97 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL714027 | 0.97 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL15591992 | 0.94 | LCK (0.70) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL10051136 | 0.94 | LCK (0.76) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL714869 | 0.94 | LCK (0.76) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL13844443 | 0.91 | LCK (0.73) | LCKALDH1A1TDP1TSHRLOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073321-B | Preparation method of 1, 4-bis [ bis (2-cyanoethyl) amino ] butane | 山东新华制药股份有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-115073321-A | Preparation method of 1, 4-bis [ bis (2-cyanoethyl) amino ] butane | 山东新华制药股份有限公司 | 2022-09-20 | — | — | CN | claimed |
| EP-2557074-A1 | Process for the preparation of N,N,N',N'-tetrakis(3-aminopropyl)-1,4-butanediamine | Astellas Pharma Inc. (JP) | 2013-02-13 | — | — | EP | claimed |
| CN-115073321-B | Preparation method of 1, 4-bis [ bis (2-cyanoethyl) amino ] butane | 山东新华制药股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-115073321-B | Preparation method of 1, 4-bis [ bis (2-cyanoethyl) amino ] butane | 山东新华制药股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-115073321-B | Preparation method of 1, 4-bis [ bis (2-cyanoethyl) amino ] butane | 山东新华制药股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-115073321-A | Preparation method of 1, 4-bis [ bis (2-cyanoethyl) amino ] butane | 山东新华制药股份有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115073321-A | Preparation method of 1, 4-bis [ bis (2-cyanoethyl) amino ] butane | 山东新华制药股份有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115073321-A | Preparation method of 1, 4-bis [ bis (2-cyanoethyl) amino ] butane | 山东新华制药股份有限公司 | 2022-09-20 | — | — | CN | disclosed |
| US-20210323844-A1 | FORMING A TREATED SWITCHABLE POLYMER AND USE THEREOF IN A FORWARD OSMOSIS SYSTEM | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2021-10-21 | — | — | US | disclosed |
| EP-2539389-B1 | AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS | RELYPSA INC (US) | 2017-12-20 | — | — | EP | disclosed |
| US-20170258825-A1 | AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS | RELYPSA, INC. | 2017-09-14 | — | — | US | disclosed |
| US-9655920-B2 | Amine polymers for use as bile acid sequestrants | RELYPSA, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| US-20140356316-A1 | AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS | RELYPSA, INC. (US) | 2014-12-04 | — | — | US | disclosed |
| EP-2557074-A1 | Process for the preparation of N,N,N',N'-tetrakis(3-aminopropyl)-1,4-butanediamine | Astellas Pharma Inc. (JP) | 2013-02-13 | — | — | EP | disclosed |
| EP-2557074-A1 | Process for the preparation of N,N,N',N'-tetrakis(3-aminopropyl)-1,4-butanediamine | Astellas Pharma Inc. (JP) | 2013-02-13 | — | — | EP | disclosed |
| EP-2539389-A1 | AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS | Relypsa, Inc. (US) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011106548-A1 | AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS | RELYPSA, INC. (US) | 2011-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170258825-A1 | AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS | NR1H4, SLC10A2, SLC10A1 | LCK 1510/4885ALDH1A1 3894/4885TDP1 3577/4885 |
| US-20140356316-A1 | AMINE POLYMERS FOR USE AS BILE ACID SEQUESTRANTS | NR1H4, SLC10A2, SLC10A1 | LCK 1510/4885ALDH1A1 3894/4885TDP1 3577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.