Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714027 | 1.00 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL17038665 | 1.00 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL15591979 | 1.00 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL15591981 | 1.00 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL15591987 | 1.00 | LCK (0.65) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL15591992 | 0.97 | LCK (0.70) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL2425755 | 0.97 | LCK (0.68) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL714869 | 0.91 | LCK (0.76) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL10051136 | 0.91 | LCK (0.76) | LCKALDH1A1TDP1TSHRLOX | |
| SCHEMBL17451526 | 0.88 | LCK (0.52) | LCKALDH1A1TDP1TSHRLOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239824-A1 | BRANCHED OR MACROCYCLIC POLYAMINES AND USES THEREOF | UNIVERSITE DE STRASBOURG (FR) | 2015-08-27 | — | — | US | disclosed |
| WO-2014029888-A2 | BRANCHED OR MACROCYCLIC POLYAMINES AND USES THEREOF | UNIVERSITE DE STRASBOURG (FR) | 2014-02-27 | — | — | WO | disclosed |
| US-8354529-B2 | Polyamine derivative and polyol derivative | BASF SE (DE) | 2013-01-15 | — | — | US | disclosed |
| EP-2511274-A2 | Polyamine derivative | BASF SE (DE) | 2012-10-17 | — | — | EP | disclosed |
| EP-2484677-A1 | Polyamine derivative | BASF SE (DE) | 2012-08-08 | — | — | EP | disclosed |
| US-20120053270-A1 | POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE | MITA NARUYOSHI (JP) | 2012-03-01 | — | — | US | disclosed |
| US-8076478-B2 | Stabilizer; photostability, heat resistance, ozone resistance, oxidation resistance, electromagnetic resistance | BASF SE (DE) | 2011-12-13 | — | — | US | disclosed |
| US-20080230743-A1 | Polyamine Derivative and Polyol Derivative | CIBA CORPORATION | 2008-09-25 | — | — | US | disclosed |
| EP-1840127-A1 | POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-10-03 | — | — | EP | disclosed |
| US-4615709-A | WITH AN ANIONIC DYE | IPPOSHA OIL INDUSTRIES CO., LTD. (JP) | 1986-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053270-A1 | POLYAMINE DERIVATIVE AND POLYOL DERIVATIVE | H1-0, H1-3, NPM1 | LCK 2455/4885ALDH1A1 4005/4885TDP1 622/4885 |
| US-20150239824-A1 | BRANCHED OR MACROCYCLIC POLYAMINES AND USES THEREOF | SRM, SMS, PNMT | LCK 1969/4885ALDH1A1 3375/4885TDP1 1604/4885 |
| US-20080230743-A1 | Polyamine Derivative and Polyol Derivative | H1-0, H1-3, H1-2 | LCK 3982/4885ALDH1A1 4203/4885TDP1 674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.