Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 18/20 | 0.85 |
| ▸ | MEN1 | O00255 | 3/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | GLA | P06280 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | STAT6 | P42226 | 1/20 | 0.70 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.70 |
| ▸ | GMNN | O75496 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | HNRNPA1 | P09651 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29363060 | 1.00 | TOP1 (0.85) | TOP1MEN1KMT2AALDH1A1GLA | |
| SCHEMBL29649464 | 1.00 | TOP1 (0.85) | TOP1MEN1KMT2AALDH1A1GLA | |
| SCHEMBL19236135 | 1.00 | TOP1 (0.85) | TOP1MEN1KMT2AALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL27410778 | 0.99 | TOP1 (0.84) | TOP1MEN1KMT2AALDH1A1GLA | |
| Ammonia Solution, Strong SCHEMBL28299902 | 0.99 | TOP1 (0.84) | TOP1MEN1KMT2AALDH1A1GLA | |
| SCHEMBL27426962 | 0.99 | TOP1 (0.84) | TOP1MEN1KMT2AALDH1A1GLA | |
| Boric Acid SCHEMBL28731501 | 0.98 | TOP1 (0.83) | TOP1MEN1KMT2AALDH1A1GLA | |
| SCHEMBL31294345 | 0.95 | TOP1 (0.80) | TOP1MEN1KMT2AALDH1A1GLA | |
| SCHEMBL10130707 | 0.94 | TOP1 (0.84) | TOP1MEN1KMT2AALDH1A1GLA | |
| SCHEMBL400254 | 0.94 | TOP1 (0.84) | TOP1MEN1KMT2AALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 937 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119950749-A | Polymer-based macromolecular prodrugs | 费城儿童医院 | 2025-05-09 | — | — | CN | claimed |
| WO-2025077823-A1 | DRUG CONJUGATE FOR INTEGRIN RECEPTOR AND USE THEREOF | 海思科医药集团股份有限公司 | 2025-04-17 | — | — | WO | claimed |
| CN-116082546-B | Aminopeptidase catalyzed hydrolysis induced charge turnover polymer and application thereof | 浙江大学 | 2025-03-11 | — | — | CN | claimed |
| EP-3595697-B1 | CLEAVABLE ESTERS FOR NANOCARRIER-BASED CANCER THERAPY | CHILDRENS HOSPITAL PHILADELPHIA (US) | 2025-02-12 | — | — | EP | claimed |
| US-20240423973-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS | LERCHEN, HANS-GEORG (DE) | 2024-12-26 | — | — | US | claimed |
| US-20240390868-A1 | PRODUCTION SYSTEM AND METHOD FOR PRODUCING NANOPARTICLES | SHANGHAI BEST-LINK BIOSCIENCE, LLC (CN) | 2024-11-28 | — | — | US | claimed |
| CN-118662648-A | GRPR targeting conjugates | 西藏海思科制药有限公司 | 2024-09-20 | — | — | CN | claimed |
| CN-118556062-A | Compounds, pharmaceutical compositions and methods for treating, preventing or managing hyperproliferative disorders | 文赛克斯制药有限责任公司 | 2024-08-27 | — | — | CN | claimed |
| CN-118511888-A | Sugarcane field weeding composition containing 7-ethylcamptothecin and saflufenacil and application thereof | 广西壮族自治区农业科学院 | 2024-08-20 | — | — | CN | claimed |
| CN-118511892-A | Rice field weeding composition containing 7-ethylcamptothecin and bensulfuron methyl and application thereof | 广西壮族自治区农业科学院 | 2024-08-20 | — | — | CN | claimed |
| WO-2002000168-A2 | COMBINATION HIV THERAPY INCLUDING CAMPTOTHECIN | SUPERGEN, INC. (US) | 2002-01-03 | — | — | WO | claimed |
| CN-1323199-A | Liposome-Encapsulated Topoisomerase Inhibitors | ALZA CORP (US) | 2001-11-21 | — | — | CN | claimed |
| EP-1121102-A1 | LIPOSOME-ENTRAPPED TOPOISOMERASE INHIBITORS | Alza Corporation (US) | 2001-08-08 | — | — | EP | claimed |
| WO-2000023052-A1 | LIPOSOME-ENTRAPPED TOPOISOMERASE INHIBITORS | ALZA CORPORATION (US) | 2000-04-27 | — | — | WO | claimed |
| EP-0758237-A1 | LACTONE STABLE FORMULATION OF CAMPTOTHECIN OR 7-ETHYL CAMPTOTHECIN | BIONUMERIK PHARMACEUTICALS, INC. (US) | 1997-02-19 | — | — | EP | claimed |
| US-5604233-A | WATER SOLUBLE ANTITUMOR, ANTICANCER AGENT | BIONUMERIK PHARMACEUTICALS, INC. (US) | 1997-02-18 | — | — | US | claimed |
| WO-1995029677-A1 | LACTONE STABLE FORMULATION OF CAMPTOTHECIN OR 7-ETHYL CAMPTOTHECIN | BIONUMERIK PHARMACEUTICALS, INC. (US) | 1995-11-09 | — | — | WO | claimed |
| EP-0296612-B1 | Camptothecin derivatives and process for preparing same | YAKULT HONSHA KK (JP) | 1994-06-22 | — | — | EP | claimed |
| EP-0296612-A1 | Camptothecin derivatives and process for preparing same | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1988-12-28 | — | — | EP | claimed |
| EP-0137145-B1 | NEW CAMPTOTHECIN DERIVATIVES AND PROCESS FOR PREPARING SAME | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1988-04-27 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240390868-A1 | PRODUCTION SYSTEM AND METHOD FOR PRODUCING NANOPARTICLES | TNF, DHPS, PPOX | TOP1 702/4885MEN1 1602/4885KMT2A 4304/4885 |
| US-20240423973-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS | PCNA, TP53, BRCA1 | TOP1 66/4885MEN1 1101/4885KMT2A 3750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.