Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12998128 | 0.93 | LMNA (0.60) | LMNAMAPTMAPK1PPARGMEN1 | |
| SCHEMBL16021262 | 0.91 | LMNA (0.62) | LMNAMAPTMAPK1PPARGMEN1 | |
| SCHEMBL2900623 | 0.91 | LMNA (0.62) | LMNAMAPTMAPK1PPARGMEN1 | |
| SCHEMBL1457039 | 0.91 | LMNA (0.62) | LMNAMAPTMAPK1PPARGMEN1 | |
| SCHEMBL13758024 | 0.88 | LMNA (0.55) | LMNAMAPTMAPK1PPARGMEN1 | |
| SCHEMBL23925002 | 0.88 | LMNA (0.56) | LMNAACE2MAPTMAPK1PPARG | |
| SCHEMBL19995790 | 0.88 | LMNA (0.56) | LMNAACE2MAPTMAPK1PPARG | |
| SCHEMBL17364263 | 0.88 | LMNA (0.56) | LMNAACE2MAPTMAPK1PPARG | |
| SCHEMBL15305641 | 0.88 | LMNA (0.56) | LMNAACE2MAPTMAPK1PPARG | |
| SCHEMBL333041 | 0.88 | LMNA (0.56) | LMNAACE2MAPTMAPK1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035318-A1 | POLYURETHANE DISPERSION, METHOD OF PRODUCING THE SAME, COATED ARTICLES, AND METHOD FOR COATING ARTICLES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-09 | — | — | US | disclosed |