Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16021262 | 1.00 | LMNA (0.62) | LMNAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL1457039 | 1.00 | LMNA (0.62) | LMNAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL12998128 | 0.98 | LMNA (0.60) | LMNAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL13758024 | 0.94 | LMNA (0.55) | LMNAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL12893068 | 0.93 | LMNA (0.53) | LMNAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL23310433 | 0.93 | TSHR (0.54) | LMNAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL12893067 | 0.92 | LMNA (0.52) | LMNAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL10048530 | 0.92 | LMNA (0.50) | LMNAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL17526393 | 0.91 | LMNA (0.48) | LMNAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL17526409 | 0.91 | LMNA (0.48) | LMNAMAPTMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101802046-B | Room temperature curable polymers and precursors thereof | DOW GLOBAL TECHNOLOGIES INC | 2014-06-18 | — | — | CN | claimed |
| EP-2516576-B1 | POLYURETHANE-BASED SEALANT FOR INSULATED GLASS UNITS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-05-16 | — | — | EP | disclosed |
| US-9546307-B2 | Polyurethane based insulated glass sealant | DOW GLOBAL TECHNOLOGIES LLC | 2017-01-17 | — | — | US | disclosed |
| US-9512262-B2 | Polyurethane dispersion, method of producing the same, coated articles, and method for coating articles | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-12-06 | — | — | US | disclosed |
| US-9330810-B2 | Synthetic ester-based dielectric fluid compositions for enhanced thermal management | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-05-03 | — | — | US | disclosed |
| EP-2751811-B1 | SYNTHETIC ESTER-BASED DIELECTRIC FLUID COMPOSITIONS FOR ENHANCED THERMAL MANAGEMENT | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-09-23 | — | — | EP | disclosed |
| US-20150218428-A1 | POLYURETHANE BASED INSULATED GLASS SEALANT | DOW GLOBAL TECHNOLOGIES LLC | 2015-08-06 | — | — | US | disclosed |
| US-9032692-B2 | Polyurethane based insulated glass sealant | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-05-19 | — | — | US | disclosed |
| EP-2638090-B1 | POLYURETHANE BASED INSULATED GLASS SEALANT | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-02-11 | — | — | EP | disclosed |
| US-8927646-B2 | Polyurethane dispersion, method of producing the same, coated articles, and method for coating articles | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-01-06 | — | — | US | disclosed |
| EP-2193154-A1 | PREPOLYMERS AND POLYMERS FOR ELASTOMERS | Dow Global Technologies Inc. (US) | 2010-06-09 | — | — | EP | disclosed |
| CN-101687975-A | Low volatiles coatings, sealants and binders from renewable oils | DOW GLOBAL TECHNOLOGIES INC | 2010-03-31 | — | — | CN | disclosed |
| US-20100048753-A1 | ALDEHYDE AND ALCOHOL COMPOSITIONS DERIVED FROM SEED OILS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-02-25 | — | — | US | disclosed |
| EP-2150566-A1 | LOW VOLATILES COATINGS, SEALANTS AND BINDERS FROM RENEWABLE OILS | Dow Global Technologies Inc. (US) | 2010-02-10 | — | — | EP | disclosed |
| US-7615658-B2 | Aldehyde and alcohol compositions derived from seed oils | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2009-11-10 | — | — | US | disclosed |
| WO-2009105351-A1 | SEPARATION OF NATURAL OIL-DERIVED ALDEHYDES OR HYDROXY METHYL ESTERS USING PROCESS CHROMATOGRAPHY | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009039130-A1 | PREPOLYMERS AND POLYMERS FOR ELASTOMERS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-03-26 | — | — | WO | disclosed |
| US-20090018300-A1 | MONOMERS AND POLYMERS FROM BIODERIVED CARBON | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2009-01-15 | — | — | US | disclosed |
| US-20090018300-A1 | MONOMERS AND POLYMERS FROM BIODERIVED CARBON | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2009-01-15 | — | — | US | disclosed |
| WO-2008134217-A1 | LOW VOLATILES COATINGS, SEALANTS AND BINDERS FROM RENEWABLE OILS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048753-A1 | ALDEHYDE AND ALCOHOL COMPOSITIONS DERIVED FROM SEED OILS | FFAR1, ALOX5, FASN | LMNA 3227/4885MAPT 1386/4885MAPK1 4228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.