Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | VNN1 | O95497 | 13/20 | 0.43 |
| ▸ | MMP1 | P03956 | 4/20 | 0.35 |
| ▸ | MMP3 | P08254 | 4/20 | 0.35 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP7 | P09237 | 2/20 | 0.33 |
| ▸ | MMP20 | O60882 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | MMP10 | P09238 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | MMP15 | P51511 | 1/20 | 0.33 |
| ▸ | MMP16 | P51512 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14602776 | 1.00 | PTGS1 (0.58) | PTGS1KCNH2VNN1MMP1MMP3 | |
| SCHEMBL7045821 | 0.80 | PTGS1 (0.79) | PTGS1KCNH2VNN1 | |
| SCHEMBL7044200 | 0.80 | PTGS1 (0.79) | PTGS1KCNH2VNN1 | |
| SCHEMBL7044196 | 0.80 | PTGS1 (0.79) | PTGS1KCNH2VNN1 | |
| SCHEMBL7045827 | 0.80 | PTGS1 (0.79) | PTGS1KCNH2VNN1 | |
| SCHEMBL6673732 | 0.80 | PTGS1 (0.56) | PTGS1KCNH2VNN1 | |
| SCHEMBL7044206 | 0.80 | PTGS1 (0.79) | PTGS1KCNH2VNN1 | |
| SCHEMBL15597028 | 0.78 | PTGS1 (0.65) | PTGS1KCNH2VNN1MMP1MMP3 | |
| SCHEMBL9691448 | 0.78 | PTGS1 (0.55) | PTGS1KCNH2VNN1MMP1MMP3 | |
| SCHEMBL7049047 | 0.77 | PTGS1 (0.62) | PTGS1KCNH2VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016072854-A2 | PANTOTHENAMIDE ANALOGUES | RADBOUD UNIVERSITAIR MEDISCH CENTRUM (NL) | 2016-05-12 | — | — | WO | disclosed |
| US-8119364-B2 | Methods for generating analogs of coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-21 | — | — | US | disclosed |
| US-20100304430-A1 | Methods for Generating Analogs of Coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-02 | — | — | US | disclosed |
| US-7727738-B2 | Methods for generating analogs of coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070128683-A1 | Metabolic delivery of coenzyme A analogs | NATIONAL SCIENCE FOUNDATION | 2007-06-07 | — | — | US | disclosed |