Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | VNN1 | O95497 | 13/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.30 |
| ▸ | MMP3 | P08254 | 2/20 | 0.30 |
| ▸ | MMP9 | P14780 | 2/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015724 | 0.82 | PTGS1 (0.50) | PTGS1KCNH2VNN1 | |
| SCHEMBL3487840 | 0.82 | PTGS1 (0.50) | PTGS1KCNH2VNN1 | |
| SCHEMBL5719421 | 0.82 | PTGS1 (0.50) | PTGS1KCNH2VNN1 | |
| SCHEMBL3487839 | 0.82 | PTGS1 (0.50) | PTGS1KCNH2VNN1 | |
| SCHEMBL5015722 | 0.82 | PTGS1 (0.50) | PTGS1KCNH2VNN1 | |
| SCHEMBL29074106 | 0.80 | PTGS1 (0.47) | PTGS1KCNH2VNN1 | |
| SCHEMBL10051718 | 0.78 | PTGS1 (0.58) | PTGS1KCNH2VNN1MMP1MMP3 | |
| SCHEMBL14602776 | 0.78 | PTGS1 (0.58) | PTGS1KCNH2VNN1MMP1MMP3 | |
| SCHEMBL29074105 | 0.77 | METAP2 (0.51) | PTGS1KCNH2VNN1 | |
| SCHEMBL29074109 | 0.77 | PTGS1 (0.45) | PTGS1KCNH2VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173112-A | Nonplugging, improved storage stability | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-22 | — | — | US | disclosed |