Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 7/20 | 0.51 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10051977 | 0.82 | CNR2 (0.46) | P2RY12EGLN2ADORA2AADORA1MEN1 | |
| SCHEMBL4265711 | 0.81 | MCL1 (0.74) | MCL1P2RY12MEN1KMT2AXDH | |
| SCHEMBL10052383 | 0.80 | P2RY12 (0.50) | P2RY12ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL4267162 | 0.77 | MCL1 (0.58) | MCL1P2RY12MEN1KMT2AXDH | |
| SCHEMBL10052381 | 0.76 | CNR2 (0.56) | P2RY12 | |
| SCHEMBL10272688 | 0.74 | HDAC3 (0.60) | MEN1KMT2ASPHK2SPHK1 | |
| SCHEMBL4263343 | 0.72 | MCL1 (0.52) | MCL1P2RY12ADORA2AADORA1MEN1 | |
| SCHEMBL3534571 | 0.70 | LMNA (0.55) | MCL1MEN1KMT2A | |
| SCHEMBL5035686 | 0.70 | MAOB (0.59) | MCL1MEN1KMT2A | |
| SCHEMBL14278777 | 0.69 | MEN1 (0.65) | MCL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019299-A1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |