Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.58 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 5/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4265711 | 0.88 | MCL1 (0.74) | MCL1P2RY12KMT2AMEN1XDH | |
| SCHEMBL19563147 | 0.85 | MCL1 (0.62) | MCL1KMT2ADHODHSLC6A2SLC6A3 | |
| SCHEMBL19563158 | 0.84 | MCL1 (0.64) | MCL1KMT2ADHODHSLC6A2SLC6A3 | |
| SCHEMBL19563151 | 0.82 | KMT2A (0.53) | MCL1KMT2AMEN1DHODHSLC6A2 | |
| SCHEMBL24859020 | 0.80 | NPC1 (0.51) | KMT2AMEN1DHODHSLC6A2SLC6A3 | |
| SCHEMBL112672 | 0.80 | MEN1 (0.59) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL19563149 | 0.77 | TDP1 (0.62) | KMT2ADHODHSLC6A2SLC6A3TDP1 | |
| SCHEMBL19563152 | 0.77 | KMT2A (0.54) | MCL1KMT2AMEN1DHODHSLC6A2 | |
| SCHEMBL10051978 | 0.77 | MCL1 (0.51) | MCL1P2RY12KMT2AMEN1XDH | |
| SCHEMBL4263343 | 0.76 | MCL1 (0.52) | MCL1P2RY12KMT2AMEN1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048258-A1 | Amide Compound | TAKEDA, PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-1845081-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048258-A1 | Amide Compound | DLAT, DGAT1, DGAT2 | MCL1 3227/4885P2RY12 4743/4885KMT2A 410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.