Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CCR1 | P32246 | 3/20 | 0.46 |
| ▸ | CCR5 | P51681 | 3/20 | 0.46 |
| ▸ | CCR8 | P51685 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30021572 | 1.00 | KDM4E (0.49) | KDM4ENPC1CYP1A2CYP2A6TSHR | |
| SCHEMBL29986334 | 1.00 | KDM4E (0.49) | KDM4ENPC1CYP1A2CYP2A6TSHR | |
| SCHEMBL23047285 | 0.93 | KDM4E (0.49) | KDM4ENPC1CYP1A2CYP2A6TSHR | |
| SCHEMBL26825177 | 0.82 | HTR2C (0.38) | KDM4ENPC1CYP1A2CYP2A6TSHR | |
| SCHEMBL6658529 | 0.81 | KDM4E (0.47) | KDM4ENPC1CYP1A2TSHRTP53 | |
| SCHEMBL21274321 | 0.81 | KDM4E (0.50) | KDM4ENPC1CYP1A2CYP2A6TSHR | |
| SCHEMBL29352216 | 0.80 | TSHR (0.65) | CYP1A2CYP2A6TSHRALDH1A1MAPT | |
| SCHEMBL2951616 | 0.80 | TSHR (0.65) | CYP1A2CYP2A6TSHRALDH1A1MAPT | |
| SCHEMBL12005378 | 0.79 | LMNA (0.47) | KDM4ECYP1A2CYP2A6TSHRALDH1A1 | |
| SCHEMBL29978362 | 0.79 | KDM4E (0.45) | KDM4ENPC1CYP1A2CYP2A6TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252624-B1 | ELECTROLUMINESCENT METAL COMPLEXES WITH DIBENZO[F,H]QUINOXALINES | UDC IRELAND LTD (IE) | 2018-07-18 | — | — | EP | disclosed |
| EP-2627732-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |
| US-9822299-B2 | Fluorine-fluorine associates | MERCK PATENT GMBH (DE) | 2017-11-21 | — | — | US | disclosed |
| EP-2802594-B1 | METAL COMPLEXES WITH DIBENZO[F,H]QUINOXALINES | UDC IRELAND LTD (IE) | 2017-04-19 | — | — | EP | disclosed |
| WO-2012007102-A1 | POLYMER MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-01-19 | — | — | WO | disclosed |