Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12006024 | 0.85 | CYP3A4 (0.42) | LMNACCR1CCR8CYP3A4CYP2A6 | |
| SCHEMBL15780759 | 0.84 | CYP2A6 (0.53) | LMNACCR1CCR8CYP3A4CYP2A6 | |
| SCHEMBL12005138 | 0.83 | CYP2A6 (0.44) | CCR1CCR8CYP3A4CYP2A6CYP1A2 | |
| SCHEMBL17589450 | 0.81 | CYP2A6 (0.50) | LMNACCR1CCR8CYP2A6CYP1A2 | |
| SCHEMBL10052072 | 0.79 | KDM4E (0.49) | LMNACCR1CCR8CYP3A4CYP2A6 | |
| SCHEMBL29986334 | 0.79 | KDM4E (0.49) | LMNACCR1CCR8CYP3A4CYP2A6 | |
| SCHEMBL30021572 | 0.79 | KDM4E (0.49) | LMNACCR1CCR8CYP3A4CYP2A6 | |
| SCHEMBL21033797 | 0.77 | ALDH1A1 (0.50) | CCR1CCR8CYP3A4CYP2A6ALDH1A1 | |
| SCHEMBL12320089 | 0.77 | NOS3 (0.54) | LMNACYP2A6METAP2NOS3NOS1 | |
| SCHEMBL2951616 | 0.77 | TSHR (0.65) | CYP3A4CYP2A6CYP1A2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822696-B2 | Ligand for asymmetric synthesis catalyst, and process for production of alpha-alkenyl cyclic compound using the same | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-09-02 | — | — | US | disclosed |
| US-20120220780-A1 | LIGAND FOR ASYMMETRIC SYNTHESIS CATALYST, AND PROCESS FOR PRODUCTION OF ALPHA-ALKENYL CYCLIC COMPOUND USING SAME | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220780-A1 | LIGAND FOR ASYMMETRIC SYNTHESIS CATALYST, AND PROCESS FOR PRODUCTION OF ALPHA-ALKENYL CYCLIC COMPOUND USING SAME | OR10J3, COASY, ACKR3 | LMNA 4389/4885CCR1 65/4885CCR8 239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.