SCHEMBL10052091

SCHEMBL10052091

FCC(CF)(c1ccc2c(c1)CN(c1ccc(F)cc1F)CO2)c1ccc2c(c1)CN(c1ccc(F)cc1F)CO2

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.34
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020835 0.86 RIPK1 (0.37) RIPK1GAAMAPTSMN1; SMN2
SCHEMBL10020839 0.86 RIPK1 (0.37) RIPK1GAAMAPTSMN1; SMN2
SCHEMBL10020842 0.86 RIPK1 (0.37) RIPK1GAAMAPTSMN1; SMN2
SCHEMBL10020840 0.86 GAA (0.38) RIPK1GAAMAPTSMN1; SMN2
SCHEMBL10020848 0.85 GAA (0.33) RIPK1GAAMAPTSMN1; SMN2
SCHEMBL10052331 0.85 RIPK1 (0.31) RIPK1
SCHEMBL10020845 0.79 ALDH1A1 (0.36) RIPK1GAAMAPTSMN1; SMN2
SCHEMBL15034015 0.77 ACACB (0.36) RIPK1GAAMAPTSMN1; SMN2
SCHEMBL10020832 0.72 RIPK1 (0.37) RIPK1GAAMAPTSMN1; SMN2
SCHEMBL10020844 0.71 HRH3 (0.33) RIPK1GAAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8119307-B2 Electrode for fuel cell, method of manufacturing the electrode, and fuel cell employing the electrode SAMSUNG SDI CO., LTD. (KR) 2012-02-21 US disclosed
US-20080145743-A1 ELECTRODE FOR FUEL CELL, METHOD OF MANUFACTURING THE ELECTRODE, AND FUEL CELL EMPLOYING THE ELECTRODE SAMSUNG SDI CO., LTD. (KR) 2008-06-19 US disclosed