Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 14/20 | 1.00 |
| ▸ | CSNK2B | P67870 | 14/20 | 1.00 |
| ▸ | CSNK2A1 | P68400 | 14/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 1/20 | 1.00 |
| ▸ | FYN | P06241 | 1/20 | 0.83 |
| ▸ | MAPT | P10636 | 5/20 | 0.75 |
| ▸ | MEN1 | O00255 | 4/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.75 |
| ▸ | RAB9A | P51151 | 3/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.75 |
| ▸ | HPGD | P15428 | 3/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.75 |
| ▸ | POLB | P06746 | 2/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.75 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30521708 | 0.91 | FYN (1.00) | CSNK2A2CSNK2BCSNK2A1ESR2FYN | |
| SCHEMBL18613228 | 0.91 | FYN (1.00) | CSNK2A2CSNK2BCSNK2A1ESR2FYN | |
| SCHEMBL29435862 | 0.90 | CSNK2A2 (0.81) | CSNK2A2CSNK2BCSNK2A1ESR2FYN | |
| SCHEMBL9663466 | 0.90 | CSNK2A2 (0.81) | CSNK2A2CSNK2BCSNK2A1ESR2FYN | |
| SCHEMBL29929667 | 0.90 | CSNK2A2 (0.81) | CSNK2A2CSNK2BCSNK2A1ESR2FYN | |
| SCHEMBL10020980 | 0.89 | CSNK2A2 (1.00) | CSNK2A2CSNK2BCSNK2A1ESR2FYN | |
| SCHEMBL31740082 | 0.86 | CSNK2A2 (1.00) | CSNK2A2CSNK2BCSNK2A1ESR2MAPT | |
| SCHEMBL31362003 | 0.86 | CSNK2A2 (1.00) | CSNK2A2CSNK2BCSNK2A1ESR2MAPT | |
| SCHEMBL312071 | 0.86 | CSNK2A2 (1.00) | CSNK2A2CSNK2BCSNK2A1ESR2MAPT | |
| SCHEMBL14697033 | 0.85 | CSNK2A2 (1.00) | CSNK2A2CSNK2BCSNK2A1ESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10391079-B2 | Methods of diagnosing and treating Alzheimer's disease with S-equol | AUSIO PHARMACEUTICALS, LLC (US) | 2019-08-27 | — | — | US | disclosed |
| US-8680140-B2 | Phytoestrogenic formulations for alleviation or prevention of menopausal symptoms | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-03-25 | — | — | US | disclosed |
| US-8680140-B2 | Phytoestrogenic formulations for alleviation or prevention of menopausal symptoms | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-03-25 | — | — | US | disclosed |
| US-8552057-B2 | Phytoestrogenic formulations for alleviation or prevention of neurodegenerative diseases | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-10-08 | — | — | US | disclosed |
| US-8552057-B2 | Phytoestrogenic formulations for alleviation or prevention of neurodegenerative diseases | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-10-08 | — | — | US | disclosed |
| US-20120269793-A1 | PHYTOESTROGENIC FORMULATIONS FOR ALLEVIATION OR PREVENTION OF HAIR LOSS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2012-10-25 | — | — | US | disclosed |
| US-20120269793-A1 | PHYTOESTROGENIC FORMULATIONS FOR ALLEVIATION OR PREVENTION OF HAIR LOSS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2012-10-25 | — | — | US | disclosed |
| US-20120164122-A1 | PHYTOESTROGENIC FORMULATIONS FOR ALLEVIATION OR PREVENTION OF NEURODEGENERATIVE DISEASES | UNIVERSITY OF SOUTHERN CALIFORNIA | 2012-06-28 | — | — | US | disclosed |
| US-20110091435-A1 | PHYTOESTROGENIC FORMULATIONS FOR ALLEVIATION OR PREVENTION OF HAIR LOSS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2011-04-21 | — | — | US | disclosed |
| US-20110091435-A1 | PHYTOESTROGENIC FORMULATIONS FOR ALLEVIATION OR PREVENTION OF HAIR LOSS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2011-04-21 | — | — | US | disclosed |
| US-20100113586-A1 | PHYTOESTROGENIC FORMULATIONS FOR ALLEVIATION OR PREVENTION OF MENOPAUSAL SYMPTOMS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2010-05-06 | — | — | US | disclosed |
| US-20100113586-A1 | PHYTOESTROGENIC FORMULATIONS FOR ALLEVIATION OR PREVENTION OF MENOPAUSAL SYMPTOMS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2010-05-06 | — | — | US | disclosed |
| US-20080108696-A1 | Phytoestrogenic Formulations for Alleviation or Prevention of Neurodegenerative Diseases | UNIVERSITY OF SOUTHERN CALIFORNIA | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120269793-A1 | PHYTOESTROGENIC FORMULATIONS FOR ALLEVIATION OR PREVENTION OF HAIR LOSS | SHBG, AR, ESR2 | CSNK2A2 2006/4885CSNK2B 1389/4885CSNK2A1 1997/4885 |
| US-10391079-B2 | Methods of diagnosing and treating Alzheimer's disease with S-equol | MFN2, FIS1, DNM1L | CSNK2A2 4390/4885CSNK2B 4619/4885CSNK2A1 4584/4885 |
| US-20100113586-A1 | PHYTOESTROGENIC FORMULATIONS FOR ALLEVIATION OR PREVENTION OF MENOPAUSAL SYMPTOMS | ESR1, GPER1, SHBG | CSNK2A2 1642/4885CSNK2B 1845/4885CSNK2A1 1472/4885 |
| US-20110091435-A1 | PHYTOESTROGENIC FORMULATIONS FOR ALLEVIATION OR PREVENTION OF HAIR LOSS | SHBG, AR, ESR2 | CSNK2A2 2006/4885CSNK2B 1389/4885CSNK2A1 1997/4885 |
| US-20080108696-A1 | Phytoestrogenic Formulations for Alleviation or Prevention of Neurodegenerative Diseases | ESR1, ESR2, SHBG | CSNK2A2 1564/4885CSNK2B 1738/4885CSNK2A1 1453/4885 |
| US-20120164122-A1 | PHYTOESTROGENIC FORMULATIONS FOR ALLEVIATION OR PREVENTION OF NEURODEGENERATIVE DISEASES | ESR2, ESR1, GPER1 | CSNK2A2 1718/4885CSNK2B 1515/4885CSNK2A1 1666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.