Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5318804 | 0.98 | CA1 (0.50) | CA1CA2HDAC7HDAC8HDAC6 | |
| SCHEMBL27969309 | 0.84 | CA1 (0.57) | CA1CA2L3MBTL1DPP7POLB | |
| SCHEMBL3693835 | 0.82 | CA2 (0.55) | CA1CA2DPP7GRIK1GRIK2 | |
| SCHEMBL1929627 | 0.82 | CA2 (0.55) | CA1CA2DPP7GRIK1GRIK2 | |
| SCHEMBL14095068 | 0.82 | CA2 (0.55) | CA1CA2DPP7GRIK1GRIK2 | |
| SCHEMBL6670118 | 0.82 | CA2 (0.55) | CA1CA2DPP7GRIK1GRIK2 | |
| SCHEMBL7934391 | 0.82 | CA2 (0.55) | CA1CA2DPP7GRIK1GRIK2 | |
| SCHEMBL28987848 | 0.80 | CA1 (0.63) | CA1CA2HDAC7HDAC8HDAC6 | |
| SCHEMBL1758553 | 0.79 | CA1 (0.50) | CA1CA2HDAC7HDAC8HDAC6 | |
| SCHEMBL7839033 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120277359-A1 | TIRE COMPONENT NOT IN CONTACT WITH AIR, BASED ON NATURAL RUBBER, A REINFORCING FILLER AND A DIHYDRAZIDE | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2012-11-01 | — | — | US | disclosed |
| US-20120270966-A1 | Composition based on natural rubber and a reinforcing inorganic filler comprising dihydrazide | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2012-10-25 | — | — | US | disclosed |
| WO-2012084821-A1 | COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2012-06-28 | — | — | WO | disclosed |