Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 14/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10052294 | 0.89 | — | — | |
| SCHEMBL17916221 | 0.88 | HCRTR2 (0.40) | HCRTR2 | |
| SCHEMBL10052293 | 0.88 | HCRTR2 (0.40) | HCRTR2 | |
| SCHEMBL10186897 | 0.81 | — | — | |
| SCHEMBL25136202 | 0.81 | HCRTR2 (0.32) | HCRTR2 | |
| SCHEMBL17471230 | 0.80 | HCRTR2 (0.32) | HCRTR2 | |
| SCHEMBL22100267 | 0.79 | HCRTR2 (0.31) | HCRTR2 | |
| SCHEMBL29317566 | 0.77 | GRM2 (0.33) | GRM2GRM3 | |
| SCHEMBL19576091 | 0.74 | HCRTR2 (0.33) | HCRTR2 | |
| SCHEMBL26393200 | 0.73 | HCRTR2 (0.34) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178531-B2 | Antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20110218175-A1 | ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2011-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218175-A1 | ANTIVIRAL AGENTS | EIF2AK2, HAVCR2, MAVS | HCRTR2 3949/4885GRM2 4378/4885GRM3 3237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.