SCHEMBL22100267

SCHEMBL22100267

CCOC1CCC(C(C)C)C1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HCRTR2 O43614 5/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL254939 0.90 SHBG (0.31)
SCHEMBL26251806 0.86 CCNT1 (0.30)
SCHEMBL11991405 0.86 HCRTR2 (0.38) HCRTR2
SCHEMBL4762344 0.86 HCRTR2 (0.38) HCRTR2
SCHEMBL17471230 0.83 HCRTR2 (0.32) HCRTR2
SCHEMBL25136202 0.79 HCRTR2 (0.32) HCRTR2
SCHEMBL10052295 0.79 HCRTR2 (0.33) HCRTR2
SCHEMBL19879603 0.77
SCHEMBL23425967 0.76 DPP4 (0.35)
SCHEMBL21466463 0.76 FFAR4 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11420934-B2 PPAR agonists THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2022-08-23 US disclosed
US-20200190019-A1 PPAR AGONISTS SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2020-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11420934-B2 PPAR agonists PPARG, PPARD, PPARA HCRTR2 2813/4885
US-20200190019-A1 PPAR AGONISTS PPARG, PPARD, PPARA HCRTR2 2813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.