Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053208 | 0.88 | CYP3A4 (0.31) | IDO1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10053282 | 0.81 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL500011 | 0.74 | CA1 (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10053280 | 0.73 | CA1 (0.43) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16920264 | 0.71 | IDO1 (0.58) | IDO1MAOB | |
| SCHEMBL10053224 | 0.69 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DMAOB | |
| SCHEMBL21968362 | 0.68 | IDO1 (0.55) | IDO1MAOB | |
| SCHEMBL21099587 | 0.68 | IDO1 (0.55) | IDO1MAOB | |
| SCHEMBL10053299 | 0.66 | ACHE (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10053203 | 0.66 | PDE4B (0.34) | PDE4APDE4BPDE4CPDE4DMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106031-B2 | Hydrolytically-resistant boron-containing therapeutics and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |