Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053283 | 0.85 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL10053203 | 0.84 | PDE4B (0.34) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL10053289 | 0.81 | IDO1 (0.31) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL500011 | 0.80 | CA1 (0.49) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL597009 | 0.79 | CA1 (0.49) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL10053280 | 0.79 | CA1 (0.43) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL13996402 | 0.78 | CA1 (0.44) | CA1CA2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL10053224 | 0.74 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL10053290 | 0.72 | CA1 (0.31) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL10053299 | 0.71 | ACHE (0.41) | PDE4APDE4BPDE4CPDE4DCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106031-B2 | Hydrolytically-resistant boron-containing therapeutics and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |