Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HAAO | P46952 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30634615 | 0.85 | TAS2R14 (0.45) | TAS2R14DHODHHDAC6RXRARXRB | |
| SCHEMBL1634606 | 0.85 | TAS2R14 (0.45) | TAS2R14DHODHHDAC6RXRARXRB | |
| SCHEMBL1235350 | 0.85 | TAS2R14 (0.49) | TAS2R14DHODHHDAC6RXRARXRB | |
| SCHEMBL9685114 | 0.85 | TAS2R14 (0.49) | TAS2R14DHODHHDAC6RXRARXRB | |
| SCHEMBL27466963 | 0.85 | TAS2R14 (0.45) | TAS2R14DHODHHDAC6RXRARXRB | |
| SCHEMBL10053350 | 0.84 | KIF11 (0.41) | TAS2R14DHODHHDAC6RXRARXRB | |
| SCHEMBL2477406 | 0.83 | TAS2R14 (0.48) | TAS2R14DHODHHDAC6RXRARXRB | |
| SCHEMBL20711420 | 0.83 | TAS2R14 (0.48) | TAS2R14DHODHHDAC6RXRARXRB | |
| SCHEMBL1223395 | 0.83 | KDM4E (0.46) | TAS2R14DHODHHDAC6RXRARXRB | |
| SCHEMBL8621898 | 0.83 | TAS2R14 (0.44) | TAS2R14DHODHHDAC6RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482203-B | Carbocyclic GLYT1 receptor antagonists | HOFFMANN LA ROCHE | 2015-06-03 | — | — | CN | disclosed |
| US-8563779-B2 | (4-trifluoromethyl-3-thiobenzoyl)cyclohexanediones and use thereof as herbicides | BAYER CROPSCIENCE AG (DE) | 2013-10-22 | — | — | US | disclosed |
| US-20120021902-A1 | (4-TRIFLUOROMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021902-A1 | (4-TRIFLUOROMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | CBR3, DDT, CYP4X1 | TAS2R14 1358/4885DHODH 283/4885HDAC6 2529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.