SCHEMBL1005335

SCHEMBL1005335

ClC[CH]Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.55
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
ARG2 P78540 1/20 0.41
CALM1 P0DP23 1/20 0.41
TSHR P16473 3/20 0.38
ALDH1A1 P00352 2/20 0.38
LOXL2 Q9Y4K0 2/20 0.38
IDO1 P14902 1/20 0.38
TP53 P04637 1/20 0.38
TRPA1 O75762 1/20 0.38
SIGMAR1 Q99720 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 1/20 0.37
RECQL P46063 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
CASP1 P29466 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL74275 0.83 MAOB (0.67) MAOBCA1CA2ARG2CALM1
SCHEMBL5438140 0.80 MAOB (0.50) MAOBCA1CA2ARG2CALM1
SCHEMBL9341670 0.77 MAOB (0.75) MAOBCA1CA2ARG2CALM1
SCHEMBL3811260 0.77 MAOB (0.75) MAOBCA1CA2ARG2CALM1
Allylbenzene SCHEMBL5807058 0.75 MAOB (0.50) MAOBCA1CA2ARG2CALM1
SCHEMBL365818 0.74 MAOB (0.55) MAOBCA1CA2ARG2CALM1
SCHEMBL185486 0.74 MAOB (0.55) MAOBCA1CA2ARG2CALM1
SCHEMBL3755335 0.74 MAOB (0.55) MAOBCA1CA2ARG2CALM1
SCHEMBL118087 0.74 MAOB (0.55) MAOBCA1CA2ARG2CALM1
SCHEMBL7301824 0.74 MAOB (0.55) MAOBCA1CA2ARG2CALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117960119-A Carbon fixing material for soil heavy metal adsorption and preparation method thereof 上海师范大学 2024-05-03 CN claimed
CN-110128052-B Concrete waterproof anti-cracking agent and preparation method thereof 陈世智 2021-04-16 CN claimed
CN-107849068-B Method for preparing polyhedral oligomeric silsesquioxanes 株式会社LG化学 2020-09-11 CN claimed
CN-107849068-A Method for preparing polyhedral oligomeric silsesquioxanes 株式会社LG化学 2018-03-27 CN claimed
EP-2060559-A1 Process for the preparation of enantiomerically pure 3-hydroxy-3-arylpropylamines and their optical stereoisomers Cadila Pharmaceuticals Limited (IN) 2009-05-20 EP claimed
CN-117960119-A Carbon fixing material for soil heavy metal adsorption and preparation method thereof 上海师范大学 2024-05-03 CN disclosed
CN-110128052-B Concrete waterproof anti-cracking agent and preparation method thereof 陈世智 2021-04-16 CN disclosed
CN-107849068-B Method for preparing polyhedral oligomeric silsesquioxanes 株式会社LG化学 2020-09-11 CN disclosed
CN-110090630-A A kind of intelligent response chiral chromatogram filler and its preparation method and application based on cyclodextrin 西南医科大学 2019-08-06 CN disclosed
CN-107849068-A Method for preparing polyhedral oligomeric silsesquioxanes 株式会社LG化学 2018-03-27 CN disclosed
CN-105965881-A Three-dimensional modeling apparatus and three-dimensional object manufacturing method 精工爱普生株式会社 2016-09-28 CN disclosed
EP-3063591-A1 LITHOGRAPHIC PRINTING PLATE PRECURSORS AND COATING Anocoil Corporation (US) 2016-09-07 EP disclosed
US-6265516-B1 UNSATURATED ESTER MODIFIED ORGANOSILICON DOW CORNING TORAY SILICONE COMPANY, LTD. 2001-07-24 US disclosed
US-6133394-A ACID CATALYTICALLY REACTING AN ORGANOCYCLOTRISILOXANE WITH AN ORGANODISILOXANE, HYDROSILATION OF END GROUPS WITH AN UNSATURATED EPOXY OR PHENOL COMPOUND REACTIVE WITH AN ORGANIC RESIN DOW CORNING TORAY SILICONE CO., LTD. (JP) 2000-10-17 US disclosed
EP-1031612-A2 Anti-staining additive and room-temperature-curable polyorganosiloxane composition Dow Corning Toray Silicone Company Ltd. (JP) 2000-08-30 EP disclosed
EP-0933387-A1 Method for preparation of organofunctional pentasiloxane, organic resin modifier and organic resins Dow Corning Toray Silicone Company, Ltd. (JP) 1999-08-04 EP disclosed
EP-0624262-B1 METHOD OF APPLYING A LACQUER FILM SENSITIVE TO UV AND/OR ELECTRON-BEAM RADIATION FRAUNHOFER GES FORSCHUNG (DE) 1998-05-06 EP disclosed
US-5506008-A Method of applying a lacquer film sensitive to ultraviolet and/or electron radiation FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1996-04-09 US disclosed
WO-1992008758-A1 SILICONE SURFACE-MODIFIED AMMONIUM POLYPHOSPHATE PPG INDUSTRIES, INC. (US) 1992-05-29 WO disclosed
US-4336395-A PROCESS FOR PREPARING (AMINOMETHYL) PHENYL-ETHYLDIMETHYLMETHOXYSILANE PETRARCH SYSTEMS, INC. (US) 1982-06-22 US disclosed