Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ARG2 | P78540 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74275 | 0.83 | MAOB (0.67) | MAOBTP53CA1CA2ARG2 | |
| SCHEMBL1741505 | 0.83 | CALM1 (0.48) | MAOBTP53CALM1KDM4ECYP3A4 | |
| SCHEMBL27834944 | 0.81 | LMNA (0.55) | MAOBTP53ALDH1A1KDM4EMAPT | |
| SCHEMBL135230 | 0.80 | MAOB (0.50) | MAOBTP53CA1CA2ARG2 | |
| SCHEMBL106848 | 0.77 | MAOB (0.75) | MAOBTP53CA1CA2ARG2 | |
| SCHEMBL18648467 | 0.77 | MAOB (0.75) | MAOBTP53CA1CA2ARG2 | |
| SCHEMBL106917 | 0.77 | MAOB (0.75) | MAOBTP53CA1CA2ARG2 | |
| SCHEMBL482781 | 0.77 | MAOB (0.46) | MAOBTP53ALDH1A1KCNH2 | |
| SCHEMBL9153358 | 0.75 | IDO1 (0.42) | ALDH1A1IDO1KCNH2 | |
| SCHEMBL2536149 | 0.75 | TP53 (0.46) | TP53ALDH1A1LOXL2TDP1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1830 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219884-A1 | PREPARATION METHOD OF ACRYLONITRILE DIMER | LG CHEM, LTD. (KR) | 2023-07-13 | — | — | US | claimed |
| EP-4144721-A1 | PREPARATION METHOD OF ACRYLONITRILE DIMER | Lg Chem, Ltd. (KR) | 2023-03-08 | — | — | EP | claimed |
| CN-115710275-A | pyrimidine-TCP compound, preparation method and medical application | 河南中医药大学 | 2023-02-24 | — | — | CN | claimed |
| CN-115557907-A | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2023-01-03 | — | — | CN | claimed |
| CN-115094704-A | Environment-friendly recyclable artificial lawn | 江苏纵横优仪人造草坪有限公司 | 2022-09-23 | — | — | CN | claimed |
| CN-110023302-B | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2022-07-26 | — | — | CN | claimed |
| CN-111978215-A | Benzyl-protected ortho-chiral amino alcohol compound and preparation method thereof | 复旦大学 | 2020-11-24 | — | — | CN | claimed |
| CN-111773214-A | Use of 2,4, 5-trisubstituted 1,2, 4-triazolones in the preparation of antiviral medicaments | 中国人民解放军军事科学院军事医学研究院 | 2020-10-16 | — | — | CN | claimed |
| CN-110191638-A | Compositions comprising particles containing cinmethylin and other herbicides | 巴斯夫农业公司 | 2019-08-30 | — | — | CN | claimed |
| CN-109553571-A | The method of chloro--methylpyridine is continuously prepared in a kind of microchannel | 内蒙古元正精细化工有限责任公司 | 2019-04-02 | — | — | CN | claimed |
| US-5364948-A | Anticancer, anticholesterol, fungicide | MERCK & CO., INC. (US) | 1994-11-15 | — | — | US | claimed |
| WO-1994018157-A1 | BIOLOGICALLY ACTIVE COMPOUNDS ISOLATED FROM AEROBIC FERMENTATION OF $i(TRICHODERMA VIRIDE) | MERCK & CO., INC. (US) | 1994-08-18 | — | — | WO | claimed |
| US-5310731-A | N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents | WHITBY RESEARCH, INC. (US) | 1994-05-10 | — | — | US | claimed |
| CN-1085546-A | Aminediol protease inhibitors | SQUIBB & SONS INC (US) | 1994-04-20 | — | — | CN | claimed |
| CN-1077842-A | Reversible agricultural gel and paste composition | DU PONT (US) | 1993-11-03 | — | — | CN | claimed |
| EP-0184550-B1 | 5-AMINO-4-HYDROXY VALERYL AMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | claimed |
| EP-0191025-B1 | N-6 AND 5'-N SUBSTITUTED CARBOXAMIDOADENOSINE DERIVATIVES AS CARDIAC VASODILATORS AND ANTIHYPERTENSIVE AGENTS, AND PROCESS FOR MAKING SAID COMPOUNDS | Whitby Research Incorporated (US) | 1990-03-07 | — | — | EP | claimed |
| EP-0191025-A1 | N-6 AND 5'-N SUBSTITUTED CARBOXAMIDOADENOSINE DERIVATIVES AS CARDIAC VASODILATORS AND ANTIHYPERTENSIVE AGENTS, AND PROCESS FOR MAKING SAID COMPOUNDS. | NELSON RES & DEV (US) | 1986-08-20 | — | — | EP | claimed |
| WO-1986000310-A1 | N-6 AND 5'-N SUBSTITUTED CARBOXAMIDOADENOSINE DERIVATIVES AS CARDIAC VASODILATORS AND ANTIHYPERTENSIVE AGENTS, AND PROCESS FOR MAKING SAID COMPOUNDS | NELSON RESEARCH AND DEVELOPMENT COMPANY (US) | 1986-01-16 | — | — | WO | claimed |
| US-3930671-A | Color former and pressure-sensitive copying paper | FUJI PHOTO FILM CO., LTD. (JA) | 1976-01-06 | — | — | US | claimed |