SCHEMBL10053398

SCHEMBL10053398

CN1C(=O)c2ccc(C(=O)c3ccc4c(c3)C(=O)N(C)C4=O)cc2C1=O

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.60
TSHR P16473 2/20 0.60
ENPP2 Q13822 1/20 0.53
APEX1 P27695 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51
POLB P06746 2/20 0.50
KDM4E B2RXH2 1/20 0.50
HPGD P15428 1/20 0.50
ATM Q13315 1/20 0.50
KMT2A Q03164 2/20 0.49
APP P05067 1/20 0.49
MEN1 O00255 1/20 0.49
MAPT P10636 1/20 0.49
ALOX15 P16050 1/20 0.49
HSD17B10 Q99714 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13183046 0.91 ALDH1A1 (0.53) ALDH1A1TSHRENPP2APEX1RXFP1
SCHEMBL13183076 0.90 ALDH1A1 (0.51) ALDH1A1TSHRENPP2APEX1RXFP1
SCHEMBL21012278 0.88 RAB9A (0.56) ALDH1A1TSHRENPP2APEX1RXFP1
SCHEMBL13159265 0.87 ALDH1A1 (0.49) ALDH1A1TSHRENPP2APEX1RXFP1
SCHEMBL17897623 0.86 NR1H2 (0.59) ALDH1A1TSHRRXFP1POLBKDM4E
SCHEMBL3942594 0.86 ALDH1A1 (0.67) ALDH1A1TSHRPOLBHPGDKMT2A
SCHEMBL7593002 0.86 CA9 (0.65) ALDH1A1TSHRAPEX1POLBHPGD
SCHEMBL10098939 0.86 ALDH1A1 (0.59) ALDH1A1APEX1POLBKMT2AMEN1
SCHEMBL2759722 0.86 APEX1 (0.48) ALDH1A1TSHRENPP2APEX1RXFP1
SCHEMBL4853822 0.85 ALDH1A1 (0.53) ALDH1A1TSHRRXFP1POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11786870-B2 CMS membrane, method for the production thereof and use thereof Forschungszentrum Jülich GmbH (DE) 2023-10-17 US disclosed
WO-2022271338-A1 AMINE-SUBSTITUTED 2-AMINO-ETHAN-1-OLYL POLYMERS, POLYIMIDES, ARTICLES, AND METHODS ESSEX FURUKAWA MAGNET WIRE USA LLC (US) 2022-12-29 WO disclosed
US-11225553-B1 Amine-substituted pyrrolidine-2,5-dionyl copolymers, polyimides, articles, and methods ESSEX FURUKAWA MAGNET WIRE USA LLC (US) 2022-01-18 US disclosed
US-20210167463-A1 POLYMER-CERAMIC HYBRID SEPARATOR MEMBRANES, PRECURSORS, AND MANUFACTURING PROCESSES CORNELL UNIVERSITY 2021-06-03 US disclosed
EP-3248230-B1 USE OF ORGANIC MOLECULES IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2020-05-06 EP disclosed
EP-2925804-B1 COPOLYMERS OF POLYAMINOPOLYOLEFINS AND POLYANHYDRIDES CHEVRON ORONITE CO (US) 2019-02-20 EP disclosed
US-20190001276-A1 COMPOSITE CARBON MOLECULAR SIEVE MEMBRANES HAVING ANTI-SUBSTRUCTURE COLLAPSE PARTICLES LOADED IN A CORE THEREOF L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2019-01-03 US disclosed
US-9999861-B2 Carbon molecular sieve membranes for nitrogen/methane separation GEORGIA TECH RESEARCH CORPORATION (US) 2018-06-19 US disclosed
US-20180147546-A1 METHOD FOR PRODUCING GAS SEPARATION COMPOSITE MEMBRANE, LIQUID COMPOSITION, GAS SEPARATION COMPOSITE MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION APPARATUS, AND GAS SEPARATION METHOD FUJIFILM CORPORATION (JP) 2018-05-31 US disclosed
US-20180071691-A1 Asymmetric Modified Carbon Molecular Sieve Hollow Fiber Membranes Having Improved Permeance AIR LIQUIDE ADVANCED TECHNOLOGIES U.S., LLC 2018-03-15 US disclosed
US-20090234092-A1 POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS XEROX CORPORATION (US) 2009-09-17 US disclosed
US-20090234092-A1 POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS XEROX CORPORATION (US) 2009-09-17 US disclosed
US-7544450-B2 Polymers of napthalene tetracarboxylic diimide dimers XEROX CORPORATION (US) 2009-06-09 US disclosed
US-7544450-B2 Polymers of napthalene tetracarboxylic diimide dimers XEROX CORPORATION (US) 2009-06-09 US disclosed
WO-2009016083-A1 DEGRADATION ACCELERATOR FOR POLYMERS AND POLYMER ARTICLE COMPRISING IT BASF SE (CH) 2009-02-05 WO disclosed
US-7449268-B2 Polycarbonates, polyesters and polyimides from the dimers exhibit properties of both binders and an electron-transporting materials; electrographic and photoconductor elements XEROX CORPORATION (US) 2008-11-11 US disclosed
US-7449268-B2 Polycarbonates, polyesters and polyimides from the dimers exhibit properties of both binders and an electron-transporting materials; electrographic and photoconductor elements XEROX CORPORATION (US) 2008-11-11 US disclosed
US-20080171275-A1 POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS XEROX CORPORATION (US) 2008-07-17 US disclosed
US-20080171275-A1 POLYMERS OF NAPTHALENE TETRACARBOXYLIC DIIMIDE DIMERS XEROX CORPORATION (US) 2008-07-17 US disclosed
US-7264637-B2 Method of inhibiting the burning of natural fibers, synthetic fibers, or mixtures thereof, or fabric or yarn composed of natural fibers, synthetic fibers, or mixtures thereof, and products produced by such methods THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2007-09-04 US disclosed