SCHEMBL10054562

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14225408	0.94	CA1 (0.39)	EGFRNPSR1CTSACA2CA1
	SCHEMBL14225424	0.89	EGFR (0.40)	EGFRNPSR1CTSACA2CA1
	SCHEMBL14225406	0.89	APP (0.40)	EGFRCA2CA1CA7CA9
	SCHEMBL14225411	0.85	ALDH1A1 (0.36)	NPSR1CTSACA2CA1CA7
	SCHEMBL18390781	0.83	PRKCI (0.33)	EGFRNPSR1CTSATHRBSMN1; SMN2
	SCHEMBL17431884	0.83	APP (0.38)	EGFRNPSR1CTSACA2CA1
	SCHEMBL15677717	0.82	ACHE (0.34)	THRBSMN1; SMN2
	SCHEMBL14225426	0.82	EGFR (0.39)	EGFRNPSR1CTSACA2CA1
	SCHEMBL14225415	0.81	APP (0.47)	EGFRNPSR1CTSACA2CA1
	SCHEMBL14225431	0.80	APP (0.46)	EGFRNPSR1CTSACA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.