Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpiperazine SCHEMBL11719034 | 0.90 | HTR6 (0.34) | HTR6 | |
| SCHEMBL23135773 | 0.87 | NCF1 (0.33) | HTR6 | |
| SCHEMBL2028323 | 0.82 | CXCR4 (0.38) | HTR6 | |
| SCHEMBL16203356 | 0.79 | CXCR4 (0.33) | — | |
| SCHEMBL1116280 | 0.77 | NCF1 (0.36) | — | |
| SCHEMBL16203354 | 0.76 | — | — | |
| SCHEMBL18013402 | 0.76 | — | — | |
| SCHEMBL24199239 | 0.75 | CXCR4 (0.31) | — | |
| SCHEMBL19237191 | 0.74 | NCF1 (0.35) | — | |
| SCHEMBL737711 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019426-A1 | PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |