Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 10/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 9/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.46 |
| ▸ | OSBP | P22059 | 3/20 | 0.46 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14552059 | 0.95 | RORC (0.51) | RORCGRIN1GRIN2AGRIN2BNR1H3 | |
| SCHEMBL12577481 | 0.86 | RORC (0.65) | RORCGRIN1GRIN2AGRIN2BNR1H3 | |
| SCHEMBL11994880 | 0.85 | RORC (0.38) | RORCNR1H3USP2LMNA | |
| SCHEMBL106036 | 0.84 | RORC (0.58) | RORCGRIN1GRIN2AGRIN2BNR1H3 | |
| SCHEMBL14902982 | 0.83 | RORC (0.51) | RORCGRIN1GRIN2AGRIN2BNR1H3 | |
| SCHEMBL10054759 | 0.83 | RORC (0.47) | RORCGRIN1GRIN2AGRIN2BNR1H3 | |
| SCHEMBL105665 | 0.82 | RORC (0.55) | RORCGRIN1GRIN2AGRIN2BNR1H3 | |
| SCHEMBL19853034 | 0.82 | RORC (0.55) | RORCGRIN1GRIN2AGRIN2BNR1H3 | |
| SCHEMBL9999687 | 0.82 | RORC (0.55) | RORCGRIN1GRIN2AGRIN2BNR1H3 | |
| SCHEMBL12248255 | 0.81 | RORC (0.58) | RORCGRIN1GRIN2AGRIN2BNR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120013837-A1 | COMPOSITION FOR FORMING LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE | SHARP KABUSHIKI KAISHA (JP) | 2012-01-19 | — | — | US | disclosed |