Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17430693 | 0.95 | RORC (0.42) | RORCLMNAPTPN1GRIN1GRIN2A | |
| SCHEMBL10017548 | 0.89 | CYP2D6 (0.41) | RORCGPBAR1HSD17B10TDP1AKR1B10 | |
| SCHEMBL10054753 | 0.87 | CYP2D6 (0.48) | RORCLMNAMEN1KMT2AOSBP | |
| SCHEMBL12577480 | 0.85 | RORC (0.51) | RORCGPBAR1HSD17B10TDP1AKR1B10 | |
| SCHEMBL11994878 | 0.84 | HMGCR (0.35) | RORCLMNAPTPN1CYP3A4MAPT | |
| SCHEMBL105231 | 0.83 | RORC (0.49) | RORCGPBAR1HSD17B10TDP1AKR1B10 | |
| SCHEMBL10054758 | 0.83 | RORC (0.57) | RORCEPHA2LMNAPTPN1GRIN1 | |
| SCHEMBL14902980 | 0.83 | RORC (0.41) | RORCLMNAMEN1KMT2APTPN1 | |
| SCHEMBL105225 | 0.81 | RORC (0.47) | RORCGPBAR1HSD17B10TDP1AKR1B10 | |
| SCHEMBL10015978 | 0.81 | RORC (0.46) | RORCGPBAR1HSD17B10TDP1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120013837-A1 | COMPOSITION FOR FORMING LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE | SHARP KABUSHIKI KAISHA (JP) | 2012-01-19 | — | — | US | disclosed |