SCHEMBL10055045

SCHEMBL10055045

Bc1ccc(-c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
ACHE P22303 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NOTUM Q6P988 2/20 0.32
POLB P06746 2/20 0.32
MAPT P10636 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
CYP2C19 P33261 2/20 0.32
HPGD P15428 2/20 0.32
MCOLN3 Q8TDD5 1/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3568731 1.00 ALDH1A1 (0.42) ALDH1A1TSHRACHETDP1NOTUM
SCHEMBL764149 0.93 ALDH1A1 (0.48) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL14402805 0.92 ALDH1A1 (0.42) ALDH1A1TSHRACHETDP1POLB
SCHEMBL16406860 0.88 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1NOTUM
SCHEMBL17409158 0.88 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1NOTUM
SCHEMBL133517 0.88 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1NOTUM
SCHEMBL13020815 0.88 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1NOTUM
SCHEMBL174956 0.88 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1NOTUM
SCHEMBL8927323 0.88 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1NOTUM
SCHEMBL6950285 0.88 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2655338-B1 BENZOIMIDAZOLE DERIVATIVES FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORP (JP) 2016-02-24 EP disclosed
US-9172051-B2 Organic light emitting host materials NITTO DENKO CORPORATION (JP) 2015-10-27 US disclosed
US-9172051-B2 Organic light emitting host materials NITTO DENKO CORPORATION (JP) 2015-10-27 US disclosed
US-8929978-B2 Phototherapy devices and methods comprising optionally substituted terphenyl and quaterphenyl compounds NITTO DENKO CORPORATION (JP) 2015-01-06 US disclosed
US-8929978-B2 Phototherapy devices and methods comprising optionally substituted terphenyl and quaterphenyl compounds NITTO DENKO CORPORATION (JP) 2015-01-06 US disclosed
US-20140066627-A1 ORGANIC LIGHT EMITTING HOST MATERIALS NITTO DENKO CORPORATION (JP) 2014-03-06 US disclosed
US-20140066627-A1 ORGANIC LIGHT EMITTING HOST MATERIALS NITTO DENKO CORPORATION (JP) 2014-03-06 US disclosed
US-8426040-B2 Compounds for use in light-emitting devices NITTO DENKO CORPORATION (JP) 2013-04-23 US disclosed
US-8426040-B2 Compounds for use in light-emitting devices NITTO DENKO CORPORATION (JP) 2013-04-23 US disclosed
US-20120197179-A1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING OPTIONALLY SUBSTITUTED TERPHENYL AND QUATERPHENYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-08-02 US disclosed
US-20120197179-A1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING OPTIONALLY SUBSTITUTED TERPHENYL AND QUATERPHENYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-08-02 US disclosed
WO-2012103380-A1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING OPTIONALLY SUBSTITUTED TERPHENYL AND QUATERPHENYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-08-02 WO disclosed
WO-2012088294-A1 BENZOIMIDAZOLE DERIVATIVES FOR USE IN LIGHT - EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-06-28 WO disclosed