SCHEMBL133517

SCHEMBL133517

Cc1ccc(N(c2ccc(C)cc2)c2ccc(N(c3ccc(C)cc3)c3ccc(-c4ccc(N(c5ccc(C)cc5)c5ccc(N(c6ccc(C)cc6)c6ccc(C)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
TSHR P16473 1/20 0.52
ACHE P22303 4/20 0.47
TDP1 Q9NUW8 2/20 0.47
MAPT P10636 3/20 0.38
CYP2C19 P33261 3/20 0.38
MCOLN3 Q8TDD5 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.38
NOTUM Q6P988 1/20 0.38
CA2 P00918 2/20 0.38
LPL P06858 1/20 0.38
LIPG Q9Y5X9 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
ENPP3 O14638 1/20 0.37
ENPP1 P22413 1/20 0.37
KIF11 P52732 1/20 0.37
NISCH Q9Y2I1 1/20 0.37
CA1 P00915 1/20 0.36
CA7 P43166 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12240220 1.00 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL17358866 1.00 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL2948631 1.00 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL174956 1.00 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL13020815 1.00 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL6950285 1.00 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL16406860 1.00 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL8927323 1.00 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL17409158 1.00 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1MAPT
SCHEMBL75876 1.00 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3762387-B1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-12 EP disclosed
EP-3251128-B1 FORMULATIONS WITH A LOW PARTICLE CONTENT MERCK PATENT GMBH (DE) 2023-06-14 EP disclosed
US-11538992-B2 Formulation of an organic functional material MERCK PATENT GMBH (DE) 2022-12-27 US disclosed
US-11211557-B2 Formulations with a low content of phenol type impurities MERCK PATENT GMBH (DE) 2021-12-28 US disclosed
EP-3464244-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-11-17 EP disclosed
US-20210147375-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-05-20 US disclosed
US-20210151679-A1 FORMULATIONS WITH A LOW CONTENT OF PHENOL TYPE IMPURITIES MERCK PATENT GMBH (DE) 2021-05-20 US disclosed
US-20210119129-A1 FORMULATIONS WITH A LOW PARTICLE CONTENT MERCK PATENT GMBH (DE) 2021-04-22 US disclosed
WO-2021074106-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-04-22 WO disclosed
EP-3532565-B1 FORMULATION OF AN ORGANIC FUNCTIONAL MATERIAL MERCK PATENT GMBH (DE) 2021-04-21 EP disclosed
US-20110288292-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2011-11-24 US disclosed
WO-2011141109-A1 ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2011-11-17 WO disclosed
US-20110108821-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2011-05-12 US disclosed
US-20110108821-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2011-05-12 US disclosed
WO-2011035835-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2011-03-31 WO disclosed
US-20110037063-A1 NOVEL MATERILS FOR ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-02-17 US disclosed
US-20110037063-A1 NOVEL MATERILS FOR ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-02-17 US disclosed
WO-2011006568-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-01-20 WO disclosed
WO-2010149259-A2 CONDUCTING FORMULATION MERCK PATENT GMBH (DE) 2010-12-29 WO disclosed
WO-2010108579-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2010-09-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288292-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES DDT, DDC, BMI1 ALDH1A1 356/4885TSHR 4869/4885ACHE 1386/4885
US-20110037063-A1 NOVEL MATERILS FOR ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, EML4, SLC40A1 ALDH1A1 428/4885TSHR 4831/4885ACHE 989/4885
US-20210147375-A1 MATERIALS FOR ELECTRONIC DEVICES PNMT, EFNA1, TES ALDH1A1 1820/4885TSHR 2839/4885ACHE 530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.