Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | NNMT | P40261 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2954974 | 0.82 | POLB (0.41) | TDP1SIRT3NNMTL3MBTL1POLB | |
| SCHEMBL2128425 | 0.82 | POLB (0.46) | TDP1SIRT3NNMTL3MBTL1POLB | |
| SCHEMBL19306320 | 0.82 | KDM4E (0.44) | TDP1SIRT3NNMTL3MBTL1BRD4 | |
| SCHEMBL27503717 | 0.80 | TDP1 (0.37) | TDP1SIRT3NNMTL3MBTL1POLB | |
| SCHEMBL8656999 | 0.80 | SIRT3 (0.37) | TDP1SIRT3NNMTL3MBTL1POLB | |
| SCHEMBL6748636 | 0.79 | SIRT3 (0.46) | TDP1SIRT3NNMTL3MBTL1POLB | |
| SCHEMBL7083041 | 0.79 | NNMT (0.50) | TDP1SIRT3NNMTL3MBTL1POLB | |
| SCHEMBL23646297 | 0.79 | KDM4E (0.45) | TDP1SIRT3NNMTL3MBTL1POLB | |
| SCHEMBL1004219 | 0.79 | KDM4E (0.50) | TDP1SIRT3NNMTL3MBTL1KDM4E | |
| SCHEMBL1259969 | 0.78 | KDM4E (0.38) | TDP1KDM4ESMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109338343-B | Chemical silver plating solution and silver plating method | 长沙理工大学 | 2020-09-25 | — | — | CN | claimed |
| JP-2011526291-A | — | — | 2011-10-06 | — | — | JP | claimed |
| EP-2331526-A2 | PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS | IRM LLC (BM) | 2011-06-15 | — | — | EP | claimed |
| US-20110112096-A1 | PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS | ITM LLC (BM) | 2011-05-12 | — | — | US | claimed |
| WO-2009158431-A2 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2009-12-30 | — | — | WO | claimed |
| CN-101516860-A | Benzoxazoles and oxazolopyridines being useful as FANUS kinases inhibitors | NOVARTIS AG (CH) | 2009-08-26 | — | — | CN | claimed |
| CN-113929719-B | Metal complex, organic electroluminescent element and consumer product thereof | 上海八亿时空先进材料有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-110198928-B | Benzyloxy-pyridinyl-cyclopropanecarboxylic acid, pharmaceutical compositions and uses thereof | 勃林格殷格翰国际有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116606568-A | Quantum dot ink composition and quantum dot electroluminescent device | 三星电子株式会社 | 2023-08-18 | — | — | CN | disclosed |
| CN-116056575-A | Substituted haloalkylsulfonanilide herbicides | FMC公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-113929719-A | Metal complex, organic electroluminescent element and consumer product thereof | 上海八亿时空先进材料有限公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-111876760-A | Chemical silver plating solution for printed circuit board and preparation method of printed circuit board | 广州市豪越新能源设备有限公司 | 2020-11-03 | — | — | CN | disclosed |
| CN-109338343-B | Chemical silver plating solution and silver plating method | 长沙理工大学 | 2020-09-25 | — | — | CN | disclosed |
| US-5891639-A | Telomerase activity assays | GERON CORPORATION (US) | 1999-04-06 | — | — | US | disclosed |
| US-5863726-A | INCUBATING CELL SAMPLE IN REACTION MIXTURE COMPRISING TELOMERASE SUBSTRATE UNDER CONDITION SUCH THAT TELOMERASE CAN CATALYZE EXTENSION OF TELOMERASE SUBSTRATE BY ADDITION OF REPEAT SEQUENCES, REPLICATING EXTENDED TELOMERASE SUBSTRATE | GERON CORPORATION (US) | 1999-01-26 | — | — | US | disclosed |
| US-5834193-A | CONTACTING DENATURED CHROMOSOMAL DNA WITH LABELED PROBE HAVING SEQUENCE COMPLEMENTARY TO A TELOMERE REPEAT SEQUENCE UNDER CONDITIONS SUCH THAT SAID PROBE HYBRIDIZES SPECIFICALLY TO TELOMERIC DNA, MEASURING BOUND PROBE, CORRELATING WITH LENGTH | GERON CORPORATION (US) | 1998-11-10 | — | — | US | disclosed |
| US-5804380-A | INCUBATION OF CELL SAMPLE, REPLICATION, MEASURING EXTENDED TELOMERASE SUBSTRATE, CORRELATION; KIT WITH BUFFER, PRIMER AND INSTRUCTIONS. | GERON CORPORATION (US) | 1998-09-08 | — | — | US | disclosed |
| EP-0774014-A1 | METHODS FOR MEASURING TELOMERE LENGTH | GERON CORPORATION (US) | 1997-05-21 | — | — | EP | disclosed |
| WO-1997015687-A1 | TELOMERASE ACTIVITY ASSAYS | GERON CORPORATION (US) | 1997-05-01 | — | — | WO | disclosed |
| WO-1996041016-A1 | METHODS FOR MEASURING TELOMERE LENGTH | GERON CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112096-A1 | PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS | IGF1R, TYMP, PDXK | TDP1 514/4885SIRT3 3816/4885NNMT 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.