SCHEMBL10055684

SCHEMBL10055684

COC(=O)C(C)(O)CNC(N)=O

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.34
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10056872 0.78 TET2 (0.39) TDP1
SCHEMBL16057010 0.78 DGAT1 (0.39) DGAT1
SCHEMBL1667377 0.75
SCHEMBL22010902 0.73
SCHEMBL74035 0.72
SCHEMBL2413071 0.72 SMN1; SMN2 (0.45) TDP1
Hydrochloric Acid SCHEMBL21963711 0.71 KDM4E (0.38) DGAT1
SCHEMBL28869957 0.70
SCHEMBL4684393 0.70
SCHEMBL10460556 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012020749-A1 TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY 塩野義製薬株式会社 (JP) 2012-02-16 WO disclosed