⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251393 | 0.97 | — | — | |
| SCHEMBL29637350 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL28201454 | 0.94 | — | — | |
| Ethylene SCHEMBL28840336 | 0.91 | TSHR (0.50) | — | |
| Methyl Alcohol SCHEMBL27865100 | 0.88 | TSHR (0.47) | — | |
| Hydrazine SCHEMBL28946830 | 0.88 | TSHR (0.47) | — | |
| Chlorobenzene SCHEMBL28111347 | 0.86 | TSHR (0.58) | — | |
| SCHEMBL28868561 | 0.86 | TSHR (0.45) | — | |
| SCHEMBL20495707 | 0.84 | CA1 (0.44) | — | |
| SCHEMBL27783827 | 0.84 | LMNA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102066002-B | Original position olefin polymerization catalyst system | PROMERUS, LLC (US) | 2015-08-26 | — | — | CN | claimed |
| CN-102066002-A | In situ olefin polymerization catalyst system | PROMERUS LLC | 2011-05-18 | — | — | CN | claimed |
| CN-117561251-A | Modulators of TREX1 | 星座制药公司 | 2024-02-13 | — | — | CN | disclosed |
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | COCRYSTAL PHARMA, INC. | 2023-05-25 | — | — | US | disclosed |
| EP-4132944-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | Cocrystal Pharma, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| CN-115698035-A | Inhibitors of norovirus and coronavirus replication | 共晶制药公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-108884070-B | Pyridyl derivatives as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2021-07-02 | — | — | CN | disclosed |
| US-10858366-B2 | Tricyclic compounds useful to treat orthomyxovirus infections | NOVARTIS AG (CH) | 2020-12-08 | — | — | US | disclosed |
| EP-3526227-A1 | BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES | Merck Patent GmbH (DE) | 2019-08-21 | — | — | EP | disclosed |
| EP-3507294-A1 | BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2019-07-10 | — | — | EP | disclosed |
| EP-3484868-A1 | METAL COMPLEXES | Merck Patent GmbH (DE) | 2019-05-22 | — | — | EP | disclosed |
| EP-1902032-A1 | PHARMACEUTICAL COMPOUNDS | Astex Therapeutics Limited (GB) | 2008-03-26 | — | — | EP | disclosed |
| WO-2006136821-A1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2006-12-28 | — | — | WO | disclosed |
| WO-2006136837-A2 | PHARMACEUTICAL COMBINATIONS COMPRISING PYRAZOLE DERIVATIVES AS PROTEIN KINASE MODULATORS | ASTEX THERAPEUTICS LIMITED (GB) | 2006-12-28 | — | — | WO | disclosed |
| EP-1706385-A1 | PYRAZOLE DERIVATIVES AS PROTEIN KINASE MODULATORS | Astex Therapeutics Limited (GB) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005061463-A1 | PYRAZOLE DERIVATIVES AS PROTEIN KINASE MODULATORS | ASTEX THERAPEUTICS LIMITED (GB) | 2005-07-07 | — | — | WO | disclosed |
| EP-0770078-A1 | 8-ARYL-1,6-NAPHTHYRIDIN-5-ONES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-05-02 | — | — | EP | disclosed |
| US-5583000-A | DETECTING PRESENCE OF RETROVIRAL PROTEASES IN SAMPLE BY COMBINING WITH SPECIFIED COMPOUND AND DETECTING PRESENCE OF COMPLEXES FORMED | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-12-10 | — | — | US | disclosed |
| WO-1996002541-A1 | 8-ARYL-1,6-NAPHTHYRIDIN-5-ONES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-02-01 | — | — | WO | disclosed |
| US-5466697-A | 8-phenyl-1,6-naphthyridin-5-ones | SYNTEX (U.S.A.) INC. (US) | 1995-11-14 | — | — | US | disclosed |