Ethylene

Ethylene

SCHEMBL28840336

C=C.Clc1ccccc1Br

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
LMNA P02545 2/20 0.50
ALDH1A1 P00352 4/20 0.40
HSD11B1 P28845 1/20 0.39
CYP2A6 P11509 4/20 0.36
CYP1A2 P05177 3/20 0.36
IGF1R P08069 1/20 0.36
MAPK1 P28482 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
PNMT P11086 1/20 0.35
IDO1 P14902 1/20 0.35
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL251393 0.94
SCHEMBL29637350 0.94
SCHEMBL1005643 0.91
Hydrazine SCHEMBL28946830 0.86 TSHR (0.47) TSHRLMNAALDH1A1HSD11B1CYP2A6
SCHEMBL28868561 0.83 TSHR (0.45) TSHRLMNAALDH1A1HSD11B1CYP2A6
SCHEMBL20495707 0.81 CA1 (0.44) TSHRLMNAALDH1A1HSD11B1CES2
SCHEMBL21267973 0.79 TSHR (0.41) TSHRLMNAALDH1A1HSD11B1CYP2A6
Isothiocyanate SCHEMBL6154362 0.79 TSHR (0.41) TSHRLMNAALDH1A1HSD11B1CYP2A6
SCHEMBL10316768 0.79 LMNA (0.41) TSHRLMNAALDH1A1HSD11B1CES2
Carbamic Acid SCHEMBL28689761 0.78 ALDH1A1 (0.46) TSHRLMNAALDH1A1CYP1A2CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459449-A Styrene-based biaxially-stretched sheet, biaxially-stretched sheet with antifogging agent layer, packaging container, and cooking method 电化株式会社 2017-02-22 CN disclosed